Knoxia valerianoides

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Tcm p52 0008.jpg
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Nomenclature

Other Names:

Historical Use of Knoxia valerianoides

Knoxia valerianoides in Traditional Chinese Medicine

Background

Hongya Daji ºìÑ¿´óêª Chinese Name (pinyin): Daji

Chinese Name  :

Common Name  :Peking Spurge Root

Specific Name  : Herba cirsii japonici/ Radix cirsii japonici

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  : To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.

Indication  :

Precautions  :

Dosage  : 9 to 15 g; for external use, appropriate quantity of the fresh herb to be pounded into paste and applied topically.

Storage  : Preserve in a ventilated and dry place.

Tcm p52 0008.jpg
P191 1.jpg

Nomenclature

Other Names:

Historical Use of Knoxia valerianoides

Knoxia valerianoides in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Hongdaji

Chinese Name  :

Common Name  :Knoxia root

Specific Name  : Radix knoxiae

Scientific Name:
Collection  : The drug is collected in autumn and winter, removed from rootlet, washed clean, treated with boiling water for a moment and dried.

Description  : Somewhat fusiform, occasionally branched, somewhat curved. 3 - 10 cm long, 0.6 - 1.2 cm in diameter. Externally reddish brown, rugged with twisted longitudinal wrinkles. Usually with small stem scar at the upper end. Texture compact, fracture reddish brown in bark and brownish yellow in wood. Odourless, tase, sweetish and pungent.

Identification  : 1.Transverse section. Cork consisting of several layers of cells. Phloem broad. Cambium in a ring. In xylem groups of vessels arranged interruptedly and radially, consisting of several rows of vessels near cambium. Gradually becoming a row of vessels scattered singly inward, rays broad. Parenchyma scattered with the mucilage cells containing rephides of calcium oxalate and secrertory cells containing reddish brown secretion.2.Boil 1 g of the powder in a test tube with 10 ml of water for 10 minutes and filter. To the filtrate add 1 drop of sodium hydroxide TS, a cherry red colour is produced which turns to orange yellow on acidifying with hydrochloric acid.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To cause drastic purgation and expel the retained water, and to counteract toxicity and induce subsidence of swelling and nodulation.

Indication  : hydrothorax and ascites with constipation and oliguria; carbuncles, sores, scrofula

Precautions  : Incompatible with Radix Glycyrrhizae. Contraindicated in pregnancy.

Dosage  : 1.5 to 3 g.

Storage  : Preserve in a cool and dry place.

Synonymns for Knoxia valerianoides

Patent Medicines and Medicines with Multiple Ingredients that include Knoxia valerianoides

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Knoxia valerianoides in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Ju-Hye Yang, Hyun Ju Do, Esther Lee, Nam-Hui Yim, Won-Kyung Cho, Kwang-Il Park, Jin Yeul Ma
Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-α/IFN-γ-induced STAT-1 and NFκB signaling in HaCaT cells.
J Ethnopharmacol: 2018, 221;48-55
[PubMed:29660465] [WorldCat.org] [DOI] (I p)

Feng Zhao, Sujuan Wang, Xiuli Wu, Yang Yu, Zhenggang Yue, Bo Liu, Sheng Lin, Chenggen Zhu, Yongchun Yang, Jiangong Shi
[Non-anthraquinones constituents from the roots of Knoxia valerianoides].
Zhongguo Zhong Yao Za Zhi: 2012, 37(14);2092-9
[PubMed:23126191] [WorldCat.org] (P p)

Feng Zhao, Sujuan Wang, Xiuli Wu, Yang Yu, Zhenggang Yue, Bo Liu, Sheng Lin, Chenggen Zhu, Yongchun Yang, Jiangong Shi
[Anthraquinones from the roots of Knoxia valerianoides].
Zhongguo Zhong Yao Za Zhi: 2011, 36(21);2980-6
[PubMed:22308688] [WorldCat.org] (P p)

Feng Zhao, Su-Juan Wang, Sheng Lin, Cheng-Gen Zhu, Shao-Peng Yuan, Xiao-Yu Ding, Zheng-Gang Yue, Yang Yu, Bo Liu, Xiu-Li Wu, Qi Hou, Jian-Gong Shi
Anthraquinones from the roots of Knoxia valerianoides.
J Asian Nat Prod Res: 2011, 13(11);1023-9
[PubMed:22007602] [WorldCat.org] [DOI] (I p)

Nam Hee Yoo, Dae Sik Jang, Yun Mi Lee, Il Ha Jeong, Jung-Hee Cho, Joo-Hwan Kim, Jin Sook Kim
Anthraquinones from the roots of Knoxia valerianoides inhibit the formation of advanced glycation end products and rat lens aldose reductase in vitro.
Arch. Pharm. Res.: 2010, 33(2);209-14
[PubMed:20195820] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects