Inula racemosa
Contents
Nomenclature
Other Names:
Historical Use of Inula racemosa
Inula racemosa in Traditional Chinese Medicine
Background
Chinese Name (pinyin): Tumuxiang
Chinese Name :
Common Name :Inula Root
Specific Name : Radix inulae
Scientific Name:
Collection : The drug is collected in autumn, remove from soil and dried in the sun.
Description : Conical slightly curved, 5 - 20 cm long. Externally yellowish brown or dark brown with longitudinal wrinkles and rootlet scars. The root stock large with sunken stem scar and remains of leaf sheath at the apex. Surrounded by cylindrical numerous rootlets. Texture hard, uneasily broken, fracture slightly even, yellowish white to pale greyish yellow, showing dented dotted oil cavities. Odour slightly aromatic, taste bitter and pungent.
Identification : 1.Transverse section: Cork consisting of several layers of cells. Phloem broad. Cambium ring less distinct. Xylem rays 6 - 25 cells wide. Vessels less frequent, singly scattered or several aggregated in groups, radiately arranged, wood fibre rare in bundle present in surroundings of vessels at the center of xylem. Parenchymatous cells containing inulin. Oil cavities scattered in phloem and xylem, 80 - 300 µm in diameter.Powder: pale yellow brown. Inulin abundant, colourless in irregular pieces. Retyiculated vessels 30 - 100 µm in diameter. Cork cells polygonal, yellowish brown. Wood fibres long fusiform with oblique ends and oblique pits.2.Heat under reflux 1 g of the powder in 5 ml of methanol for 5 minutes and filter. To 1 ml of the filtrate add slowly 0.5 ml of sulfuric acid along the tube wall. A brownish red ring is produced at the junction of the two layers.3.To 0.5g of the powder add 4 ml of methanol, tightly stoppered, shake aloow to stand for 30 minutes and filter. Use the filtrate in the test solution. Dissolve alantolactone CRS and isoalantolactone CRS in mtehanol to produced a solution containing 2 mg of each per ml use as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B), using silica gel G containing 0.25% silver nitrate as the coating substance and petroleum ether (60 - 90ºC)-benzene-ethyl acetate (75:15:15) as the mobile phase. Apply separately to the plate 5 µl of each of the two solutions. After developing, protected from light and removal of the plate, dry it in the air. Spray with 5% anisaldehyde-sulfuric acid solution. Visualize under a current of hot air. The two bluish violet spots in the chromatogram obtained with the test solution correspond in position and colour to the spots in the chromatogram obtained with the reference solution.
Processing : Eliminate foreign matter, wash clean, soften thoroughly, cut into slices and dry in the sun.
Action : To invigorate the spleen and regulate the function of stomach, to relieve the depression of the liver qi, to alleviate pain, and to prevent abortion.
Indication :
Precautions :
Dosage : 3 to 9 g, mostly used in making pills or powder.
Storage : Preserve in a cool and dry place.
Synonymns for Inula racemosa
Patent Medicines and Medicines with Multiple Ingredients that include Inula racemosa
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Inula racemosa in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Cong Guo, Ruo-Yu Qi, Jie-Yi Ren, Dan-Dan Xu, Qiang Zhang, Jin-Ming Gao, Jiang-Jiang Tang
##Title##
J Org Chem: 2024, 89(7);5029-5037
[PubMed:38531374]
[WorldCat.org]
[DOI]
(I p)
Bonsa Hussein Ahmed, Mekonnen Abebayehu Desta, Ashenafi Alemu Wami, Getachew Tesfaye Beyene, Kibrom Gebreheiwot Bedane
Sesquiterpene Acids and Lactones from Inula Confertiflora with their Antibacterial Activities.
Chem Biodivers: 2024;e202400265
[PubMed:38470349]
[WorldCat.org]
[DOI]
(I a)
Jin Se Kim, Jin Hee Kim, Hyeyoon Eo, In Gyoung Ju, So-Ri Son, Ji-Woon Kim, Dae Sik Jang, Myung Sook Oh
Inulae Flos has Anti-Depressive Effects by Suppressing Neuroinflammation and Recovering Dysfunction of HPA-axis.
Mol Neurobiol: 2024;
[PubMed:38457106]
[WorldCat.org]
[DOI]
(I a)
Chengyun Dou, Hongbo Zhu, Xia Xie, Cuiqin Huang, Chuangjie Cao
Integrated Pharmaco-Bioinformatics Approaches and Experimental Verification To Explore the Effect of Britanin on Nonalcoholic Fatty Liver Disease.
ACS Omega: 2024, 9(7);8274-8286
[PubMed:38405493]
[WorldCat.org]
[DOI]
(I e)
Hanieh Noormohamadi, Maryam Hamzeloo-Moghadam, Davood Bashash, Maryam Kargar, Mehrdad Izadirad, Seyedeh Zahra Hasanpour, Ahmad Gharehbaghian
Gaillardin exerts potent antileukemic effects on HL-60 cells and intensifies arsenic trioxide cytotoxicity: Providing new insight into sesquiterpene lactones in leukaemia treatment.
Clin Exp Pharmacol Physiol: 2024, 51(4);e13847
[PubMed:38382534]
[WorldCat.org]
[DOI]
(I p)
