Inula britannica var. chinensis

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Nomenclature

Other Names:

Historical Use of Inula britannica var. chinensis

Inula britannica var. chinensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Xuanfuhua

Chinese Name  :

Common Name  :Inula Flower

Specific Name  : Flos inulae

Scientific Name:
Collection  : The drug is collected in summer and autumn at flowering, remove foreign matter and dried in the sun or in the shade.

Description  : Oblate subspherical, 1 - 2cm in diameter, involucre consisting of numerous bracts, imbricated, bracts lanceolate or strip-shaped, greyish yellow, 4 - 11mm long. Sometimes pedicels remaining at the base of involucre, surfaces of the bracts and pedicels covered with white hairs. Ligulate florets 1 row, yellow about 1cm long , mostly rolled, often fallen, with 3 terminal teeth, tubular florets numerous, brownish-yellow, about 5mm long with 5 terminal teeth, numerous white pappi occurring in the apex of ovary, 5 - 6mm long. Small elliptical schene sometimes visible, texture light, easily broken and separated, odour slight, taste slightly bitter.

Identification  : Surface view of various parts, non-glandular hairs of bracts 1-8 celled, base of the multicellular ones large and the apical cells especially long, the inner rows of bracts bearing 2 - 3 celled seriate non-glandular hairs. Pappus consisting of multiseriate non-glandular hairs, margin cells slightly convex. Epidermal cells of ovary containing cylindrical crystals of calcium oxalate up to 48µm long, 2 - 5µm in diameter, non-glandular hairs of ovary biseriated. 90 - 220µm long. Glandular hairs of the bracts and corolla clavate with multi-cellular head, mostly biseriate, covered with cuticle sac, stalk multicellular, biseriate, pollen grains subspherical, 22 - 23µm in diameter, exine spiny about 3µm long with three germinal pores.

Processing  : Eliminate pedicels, leaves and foreign matter.Processed with honey: Stir fry (cleaned) as describe under the method for stir frying with honey (Appendix ll D) until it is no longer sticky to the fingers.

Action  : To relieve cough, eliminate phlegm, promote diuresis, and arrest vomiting.

Indication  : cough in common cold; cough with dyspnea and copious expectoration due to accumulation of phlegm; belching nausea and vomiting with stuffiness sensation in the epigastric region

Precautions  :

Dosage  : 3 to 9 g, to be wrapped in making decoction.

Storage  : Preserve in a dry place, protected from moisture.

Synonymns for Inula britannica var. chinensis

Patent Medicines and Medicines with Multiple Ingredients that include Inula britannica var. chinensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Inula britannica var. chinensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Kung-Woo Nam, Goo Taeg Oh, Eun-Kyoung Seo, Kyeong Ho Kim, Uk Koo, Sung-Jin Lee, Woongchon Mar
Nuclear factor kappaB-mediated down-regulation of adhesion molecules: possible mechanism for inhibitory activity of bigelovin against inflammatory monocytes adhesion to endothelial cells.
J Ethnopharmacol: 2009, 123(2);250-6
[PubMed:19429369] [WorldCat.org] [DOI] (I p)

Naisheng Bai, Ching-Shu Lai, Kan He, Zhu Zhou, Li Zhang, Zheng Quan, Nanqun Zhu, Qun Yi Zheng, Min-Hsiung Pan, Chi-Tang Ho
Sesquiterpene lactones from Inula britannica and their cytotoxic and apoptotic effects on human cancer cell lines.
J. Nat. Prod.: 2006, 69(4);531-5
[PubMed:16643020] [WorldCat.org] [DOI] (P p)

Hui Zi Jin, Dongho Lee, Jeong Hyung Lee, Kyeong Lee, Young-Soo Hong, Dong-Ho Choung, Young Ho Kim, Jung Joon Lee
New sesquiterpene dimers from Inula britannica inhibit NF-kappaB activation and NO and TNF-alpha production in LPS-stimulated RAW264.7 cells.
Planta Med.: 2006, 72(1);40-5
[PubMed:16450294] [WorldCat.org] [DOI] (P p)

Yong Jin Song, Dae Young Lee, Su-Nam Kim, Kang Ro Lee, Hyang Woo Lee, Jeung-Whan Han, Dong-Won Kang, Hoi Young Lee, Yong Kee Kim
Apoptotic potential of sesquiterpene lactone ergolide through the inhibition of NF-kappaB signaling pathway.
J. Pharm. Pharmacol.: 2005, 57(12);1591-7
[PubMed:16354403] [WorldCat.org] [DOI] (P p)

Kang-Hoon Je, Ah-Reum Han, Hyun-Tai Lee, Woongchon Mar, Eun-Kyoung Seo
The inhibitory principle of lipopolysaccharide-induced nitric oxide production from Inula britannica var. chinensis.
Arch. Pharm. Res.: 2004, 27(1);83-5
[PubMed:14969344] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects