Ilex cornuta

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P300 2.jpg

Nomenclature

Other Names:

Historical Use of Ilex cornuta

Ilex cornuta in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Gouguye

Chinese Name  :

Common Name  :Chinese Holly Leaf

Specific Name  : Folium ilicis cornutae

Scientific Name:
Collection  : The drug is collected in autumn, removed from foreign matter and dried in the sun.

Description  : Subrectangular, ocassionally long ovate, 3 - 8cm long, 1.5 - 4cm wide. Apex with 3 relatively big hard spines, the apical one usually recurved, base trunctate or broadly cuneate, sometimes both sides with 1 - 3 spines, edges somewhat recurved, long ovate leaves usually absent from spines. Upper surface yellowish green or greenish brown, lustrous, lower surface greyish yellow or greyish green. Viens pinnate, petioles short, texture leathery, hard and thick, odorless, taste slightly bitter.

Identification  : Transverse section at the base of the leaf, upper epidermal cells subsquare, thick walled covered with a thick cuticle bearing unicellular non-glandular hairs nearmidrib. Lower epidermal cells relatively small, stomata visible. Palisade tissue of 2 - 4 rows of cells, spongy tissue loose, 1 to numerous of collenchymatous cells occurring inside the upper and lower epidermis at midrib. Vascular bundle midrib collateral with lignified fibre groups above and below the vascular bundle. Collenchymatous cells, semi ring of stone cells and lignified fibre groups sequently occurringg inside the epidermis of margin, several tows of collenchymatous cells at the margin near the petioles, absent above the base. Stone cells ocassionally occurring in the collenchyma inside the epidermis of margin and the lower epidermis of midrib and outside the fibre groups below the phloem. Parenchyma and lower epidermis frequently containing clusters of calcium oxalate.

Processing  :

Action  : To remove heat, to subdue th ehyperactivity of the liver, and to replenish the kidney yin.

Indication  : hemoptysis and afternoon fever in phtisis; dizziness, hypertension

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a dry place.

P300 2.jpg

Nomenclature

Other Names:

Historical Use of Ilex cornuta

Ilex cornuta in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Gouguye

Chinese Name  :

Common Name  :Chinese Holly Leaf

Specific Name  : Folium ilicis cornutae

Scientific Name:
Collection  : The drug is collected in autumn, removed from foreign matter and dried in the sun.

Description  : Subrectangular, ocassionally long ovate, 3 - 8cm long, 1.5 - 4cm wide. Apex with 3 relatively big hard spines, the apical one usually recurved, base trunctate or broadly cuneate, sometimes both sides with 1 - 3 spines, edges somewhat recurved, long ovate leaves usually absent from spines. Upper surface yellowish green or greenish brown, lustrous, lower surface greyish yellow or greyish green. Viens pinnate, petioles short, texture leathery, hard and thick, odorless, taste slightly bitter.

Identification  : Transverse section at the base of the leaf, upper epidermal cells subsquare, thick walled covered with a thick cuticle bearing unicellular non-glandular hairs nearmidrib. Lower epidermal cells relatively small, stomata visible. Palisade tissue of 2 - 4 rows of cells, spongy tissue loose, 1 to numerous of collenchymatous cells occurring inside the upper and lower epidermis at midrib. Vascular bundle midrib collateral with lignified fibre groups above and below the vascular bundle. Collenchymatous cells, semi ring of stone cells and lignified fibre groups sequently occurringg inside the epidermis of margin, several tows of collenchymatous cells at the margin near the petioles, absent above the base. Stone cells ocassionally occurring in the collenchyma inside the epidermis of margin and the lower epidermis of midrib and outside the fibre groups below the phloem. Parenchyma and lower epidermis frequently containing clusters of calcium oxalate.

Processing  :

Action  : To remove heat, to subdue th ehyperactivity of the liver, and to replenish the kidney yin.

Indication  : hemoptysis and afternoon fever in phtisis; dizziness, hypertension

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a dry place.

Synonymns for Ilex cornuta

Patent Medicines and Medicines with Multiple Ingredients that include Ilex cornuta

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ilex cornuta in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Chunxi Yang, Jinyong Xiong
##Title##
Plant Dis: 2023;
[PubMed:37981569] [WorldCat.org] [DOI] (P a)

Ki-Kwang Oh, Sang-Jun Yoon, Su-Been Lee, Sang Youn Lee, Haripriya Gupta, Raja Ganesan, Satya Priya Sharma, Sung-Min Won, Jin-Ju Jeong, Dong Joon Kim, Ki-Tae Suk
The juxtaposition of Ilex cornuta fruit and gut microbiota against alcoholic liver disease based on the integrated pharmacology via metabolomics.
Clin Transl Med: 2023, 13(9);e1392
[PubMed:37670478] [WorldCat.org] [DOI] (I p)

Biao Wang, Hao Li, Tianyu Chen, Wei Wei, Guiyou Liu, Weiqing Huang, Bo He, Yonghao Ye, Wei Yan
##Title##
Nat Prod Res: 2024, 38(9);1478-1486
[PubMed:36451585] [WorldCat.org] [DOI] (I p)

Xi Zheng, Jingyi Wang, Junlin Zhou, Dong Wang
##Title##
Drug Des Devel Ther: 2022, 16;2569-2587
[PubMed:35959419] [WorldCat.org] [DOI] (I e)

Yawei Que, Donghai Huang, Shuangjun Gong, Xuejiang Zhang, Bin Yuan, Minfeng Xue, Wenqi Shi, Fansong Zeng, Meilin Liu, Tingting Chen, Dazhao Yu, Xia Yan, Zhengyi Wang, Lijun Yang, Libo Xiang
##Title##
Front Cell Infect Microbiol: 2022, 12;898500
[PubMed:35860382] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects