Ilex cornuta

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P300 2.jpg

Nomenclature

Other Names:

Historical Use of Ilex cornuta

Ilex cornuta in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Gouguye

Chinese Name  :

Common Name  :Chinese Holly Leaf

Specific Name  : Folium ilicis cornutae

Scientific Name:
Collection  : The drug is collected in autumn, removed from foreign matter and dried in the sun.

Description  : Subrectangular, ocassionally long ovate, 3 - 8cm long, 1.5 - 4cm wide. Apex with 3 relatively big hard spines, the apical one usually recurved, base trunctate or broadly cuneate, sometimes both sides with 1 - 3 spines, edges somewhat recurved, long ovate leaves usually absent from spines. Upper surface yellowish green or greenish brown, lustrous, lower surface greyish yellow or greyish green. Viens pinnate, petioles short, texture leathery, hard and thick, odorless, taste slightly bitter.

Identification  : Transverse section at the base of the leaf, upper epidermal cells subsquare, thick walled covered with a thick cuticle bearing unicellular non-glandular hairs nearmidrib. Lower epidermal cells relatively small, stomata visible. Palisade tissue of 2 - 4 rows of cells, spongy tissue loose, 1 to numerous of collenchymatous cells occurring inside the upper and lower epidermis at midrib. Vascular bundle midrib collateral with lignified fibre groups above and below the vascular bundle. Collenchymatous cells, semi ring of stone cells and lignified fibre groups sequently occurringg inside the epidermis of margin, several tows of collenchymatous cells at the margin near the petioles, absent above the base. Stone cells ocassionally occurring in the collenchyma inside the epidermis of margin and the lower epidermis of midrib and outside the fibre groups below the phloem. Parenchyma and lower epidermis frequently containing clusters of calcium oxalate.

Processing  :

Action  : To remove heat, to subdue th ehyperactivity of the liver, and to replenish the kidney yin.

Indication  : hemoptysis and afternoon fever in phtisis; dizziness, hypertension

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a dry place.

P300 2.jpg

Nomenclature

Other Names:

Historical Use of Ilex cornuta

Ilex cornuta in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Gouguye

Chinese Name  :

Common Name  :Chinese Holly Leaf

Specific Name  : Folium ilicis cornutae

Scientific Name:
Collection  : The drug is collected in autumn, removed from foreign matter and dried in the sun.

Description  : Subrectangular, ocassionally long ovate, 3 - 8cm long, 1.5 - 4cm wide. Apex with 3 relatively big hard spines, the apical one usually recurved, base trunctate or broadly cuneate, sometimes both sides with 1 - 3 spines, edges somewhat recurved, long ovate leaves usually absent from spines. Upper surface yellowish green or greenish brown, lustrous, lower surface greyish yellow or greyish green. Viens pinnate, petioles short, texture leathery, hard and thick, odorless, taste slightly bitter.

Identification  : Transverse section at the base of the leaf, upper epidermal cells subsquare, thick walled covered with a thick cuticle bearing unicellular non-glandular hairs nearmidrib. Lower epidermal cells relatively small, stomata visible. Palisade tissue of 2 - 4 rows of cells, spongy tissue loose, 1 to numerous of collenchymatous cells occurring inside the upper and lower epidermis at midrib. Vascular bundle midrib collateral with lignified fibre groups above and below the vascular bundle. Collenchymatous cells, semi ring of stone cells and lignified fibre groups sequently occurringg inside the epidermis of margin, several tows of collenchymatous cells at the margin near the petioles, absent above the base. Stone cells ocassionally occurring in the collenchyma inside the epidermis of margin and the lower epidermis of midrib and outside the fibre groups below the phloem. Parenchyma and lower epidermis frequently containing clusters of calcium oxalate.

Processing  :

Action  : To remove heat, to subdue th ehyperactivity of the liver, and to replenish the kidney yin.

Indication  : hemoptysis and afternoon fever in phtisis; dizziness, hypertension

Precautions  :

Dosage  : 9 to 15 g.

Storage  : Preserve in a dry place.

Synonymns for Ilex cornuta

Patent Medicines and Medicines with Multiple Ingredients that include Ilex cornuta

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ilex cornuta in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Shu-Juan Yu, Zhi-Pu Yu, Yin-Yin Wang, Jie Bao, Tao Yuan, Jin-Hai Yu, Hua Zhang
##Title##
J Asian Nat Prod Res: 2020, 22(4);316-328
[PubMed:30821481] [WorldCat.org] [DOI] (I p)

Hai-Xia Zhan, Juan Li, Han-Li Ruan, Peng Zhang, Hui-Fang Pi
Two New Ursane-type Triterpenoid Glycosides from Ilex Cornuta.
Curr Med Sci: 2018, 38(6);976-981
[PubMed:30536058] [WorldCat.org] [DOI] (I p)

Anna Maria Vettraino, Hong-Mei Li, Rene Eschen, Carmen Morales-Rodriguez, Andrea Vannini
The sentinel tree nursery as an early warning system for pathway risk assessment: Fungal pathogens associated with Chinese woody plants commonly shipped to Europe.
PLoS ONE: 2017, 12(11);e0188800
[PubMed:29186190] [WorldCat.org] [DOI] (I e)

Jisu Kim, Wonku Kang, Hyeyoung Min
In Vitro Anti-Inflammatory Activity of Ilex cornuta Extract Mediated by Inhibition of Extracellular Signal-Regulated Kinase Phosphorylation.
J Med Food: 2017, 20(10);981-988
[PubMed:28854336] [WorldCat.org] [DOI] (I p)

Yan Yuan, Shu Pan, Shi-Lin Yang, Yan-Li Liu, Qiong-Ming Xu
Antioxidant and cardioprotective effects of Ilex cornuta on myocardial ischemia injury.
Chin J Nat Med: 2017, 15(2);94-104
[PubMed:28284430] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects