Houttuynia cordata

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Other Names:

Historical Use of Houttuynia cordata

Houttuynia cordata in Traditional Chinese Medicine


Chinese Name (pinyin): Yuxingcao

Chinese Name  :

Common Name  :Houttuynia

Specific Name  : Herba houttuyniae

Scientific Name:
Collection  : The drug is collected in summer when the plant growing luxuriantly, removed from foreign matter and dried in the sun.

Description  : Stems flattened-cylindrical, twisted, 20 - 35cm long, 2 - 3mm in diameter, externally brownish yellow with several longitudinal ridges and distinct nodes. The nodes on the lower part bearing remains of fibrous roots. Textur fragile and easily broken. Leaves alternate, lamina rolled and crumpled when whole, cordate 3 - 5cm long, 3 - 4.5cm wide. Apex acuminate, margins entire, the upper surface dartk yellowish green to dark brown, the lower surface greyish green or greyish brown, petioles slender, accreted with a stipule at the base, forming a sheath. Spike terrminal, yellowish brown, odour fishy on rubbing, taste slightly astringrent.

Identification  : (1) Place a quantity of the powder into a test tube, press tightly with a glass rod, add few drops of fuchsine-sulfurous acid TS to moisten the powder at the upper part, stand for a moment. Observe through the tube wall, the moisten powder shows a pink or reddish violet color.(2). Heat under reflux 1g of the powder with 10ml of ethanol for 10 minutes and filter. To 2ml of the filtrate add small quantity of magnesium powder and 3 drops of hydrochloric acid, heat on a water bath, a red colour is produced.(3) To 25g of the drug, cut into pieces, in a rounded-bottom flask, add 250ml of water and connect a volatile oil determination tube.. Add water through the top of the tube until the granulated tube is filled. Add further 1ml of ethyl acetate, connect the tube to a reflux condenser. Heat the flask under reflux for 4 hours then allow it to stand for a few minutes, collect the ethyl acetate layer as the test solution. Dissolve methyl nonyl ketone in ethyl acetate to produce a solution containing 10µg per ml as the reference solution. Carry out the method for thin layer chromatography (Appendix Vl B) using silica gel G as the coating substance and n-hexane-ethyl acetate (9:1) as the reference solution. Apply separately to the plate 5µl of the test solution and 2µl of the reference solution. After developing and removal of the plate, dry it in air, spray with dinitrohydrazine TS. The yellow spot in the chromatogram obtained with the test solution correspond in position and color to the spot in the chromatogram obtained with the reference solution.

Processing  : Eliminate foreign matter, wash rapidly, cut into sections and dry in the sun.

Action  : To remove toxic heat, to promote the drainange of pus, and to relieve dysuria.

Indication  : lung abscess with purulent expectoration; heat in the lung with cough and dyspnea; acute dysentery; acute urinary tract infection; carbuncles and sores;

Precautions  :

Dosage  : 15 to 20 gto be boiled briefly; 30 to 50 g of the fresh herb to be decocted or pounded to make juice for oral administration. For external use, appropriate quantity to be pounded into paste for topical application or made in hot decoction for fuming and w

Storage  : Preserve in a dry place.

Synonymns for Houttuynia cordata

Patent Medicines and Medicines with Multiple Ingredients that include Houttuynia cordata

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Houttuynia cordata in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Li-Jun Ling, Yan Lu, Yun-Yi Zhang, Hai-Yan Zhu, Peng Tu, Hong Li, Dao-Feng Chen
Flavonoids from Houttuynia cordata attenuate H1N1-induced acute lung injury in mice via inhibition of influenza virus and Toll-like receptor signalling.
Phytomedicine: 2019, 67;153150
[PubMed:31958713] [WorldCat.org] [DOI] (I a)

Taiyo Toriba, Hiroki Tokunaga, Kazuma Nagasawa, Fanyu Nie, Akiko Yoshida, Junko Kyozuka
Suppression of Leaf Blade Development by BLADE-ON-PETIOLE Orthologs Is a Common Strategy for Underground Rhizome Growth.
Curr. Biol.: 2020, 30(3);509-516.e3
[PubMed:31956025] [WorldCat.org] [DOI] (I p)

Naphakorn Srichaiyo, Sudaporn Tongsiri, Seyed Hossein Hoseinifar, Mahmoud A O Dawood, Maria Ángeles Esteban, Einar Ringø, Hien Van Doan
The effect of fishwort (Houttuynia cordata) on skin mucosal, serum immunities, and growth performance of Nile tilapia.
Fish Shellfish Immunol.: 2020, 98;193-200
[PubMed:31923565] [WorldCat.org] [DOI] (I a)

Michael Basic, Fabian Elgner, Daniela Bender, Catarina Sabino, Marie-Luise Herrlein, Hanna Roth, Mirco Glitscher, Alicia Fath, Thomas Kerl, Hans-Günther Schmalz, Eberhard Hildt
A synthetic derivative of houttuynoid B prevents cell entry of Zika virus.
Antiviral Res.: 2019, 172;104644
[PubMed:31697958] [WorldCat.org] [DOI] (I p)

Yakui Chen, Qifa Zhu, Xiangzhou Dong, Weiwei Huang, Chenyu Du, Diannan Lu
How Serratia marcescens HB-4 absorbs cadmium and its implication on phytoremediation.
Ecotoxicol. Environ. Saf.: 2019, 185;109723
[PubMed:31586845] [WorldCat.org] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects