Glehnia littoralis

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Nomenclature

Other Names:

Historical Use of Glehnia littoralis

Glehnia littoralis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Beishashen

Chinese Name  :

Common Name  :Glehnia Root

Specific Name  : Radix glehniae

Scientific Name:
Collection  : The drug is collected in summer and autumn removed from rootlets, washed clean, dried slightly in the air, treated with boiling water peeled and dried or dried immediately directly after washing.

Description  : Slenderly cylindrical, branching occasionally, 15 - 45 cm long. 0.4 - 1.2 cm in diameter. Externally yellowish white, slightly rough, occasionally with patches of cork adhering or yellowish brown when un-peeled, finely wrinkled longitudinally and with brownish yellow spotted rootlet scars. Top with yellowish brown remains of rhizome. The upper part somewhat thin, the middle part relatively thick and the lower part tapering. Texture fragile, easily broken. Fracture yellowish white in bark and yellow in wood. Odour characteristic, taste sweetish.

Identification  : Transverse section: Cortex of several layers of parenchymatous cells, scattered with secretory canals. Cork visible when unpeeled. Phloem broad, rays distinct, sieve tubes groups collapsed in the outer part and appearing as a narrow band. Secretory canals scattered. 20 - 65 µm in diameter, containing yellow-brown secretion, surrounded by 5 - 8 secretory cells. Cambium in a ring. Xylem rays 2 - 5 cells wide, most vessels arrange in V-shaped. Parenchymatous cells containing gelatinized starch granules.

Processing  : Remove remains of the stem and foreign matter, soften slightly cut into sections and dry.

Action  : To replenish yin of the lung and stomach, remove heat from the lung, and promote fluid secretion.

Indication  : dry codugh caused by heat in the lung; bloody sputum in phtisis; thirst in febrile diseases

Precautions  : Incompatible with Rhizoma et Radix Veratri.

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a ventilated and dry place, protected from moth.

P123 1.jpg

Nomenclature

Other Names:

Historical Use of Glehnia littoralis

Glehnia littoralis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Beishashen

Chinese Name  :

Common Name  :Glehnia Root

Specific Name  : Radix glehniae

Scientific Name:
Collection  : The drug is collected in summer and autumn removed from rootlets, washed clean, dried slightly in the air, treated with boiling water peeled and dried or dried immediately directly after washing.

Description  : Slenderly cylindrical, branching occasionally, 15 - 45 cm long. 0.4 - 1.2 cm in diameter. Externally yellowish white, slightly rough, occasionally with patches of cork adhering or yellowish brown when un-peeled, finely wrinkled longitudinally and with brownish yellow spotted rootlet scars. Top with yellowish brown remains of rhizome. The upper part somewhat thin, the middle part relatively thick and the lower part tapering. Texture fragile, easily broken. Fracture yellowish white in bark and yellow in wood. Odour characteristic, taste sweetish.

Identification  : Transverse section: Cortex of several layers of parenchymatous cells, scattered with secretory canals. Cork visible when unpeeled. Phloem broad, rays distinct, sieve tubes groups collapsed in the outer part and appearing as a narrow band. Secretory canals scattered. 20 - 65 µm in diameter, containing yellow-brown secretion, surrounded by 5 - 8 secretory cells. Cambium in a ring. Xylem rays 2 - 5 cells wide, most vessels arrange in V-shaped. Parenchymatous cells containing gelatinized starch granules.

Processing  : Remove remains of the stem and foreign matter, soften slightly cut into sections and dry.

Action  : To replenish yin of the lung and stomach, remove heat from the lung, and promote fluid secretion.

Indication  : dry codugh caused by heat in the lung; bloody sputum in phtisis; thirst in febrile diseases

Precautions  : Incompatible with Rhizoma et Radix Veratri.

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a ventilated and dry place, protected from moth.

Synonymns for Glehnia littoralis

Patent Medicines and Medicines with Multiple Ingredients that include Glehnia littoralis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Glehnia littoralis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Changcheng Lu, Chen Huang, Shuhui Qu, Huiyuan Lin, Hai-Jing Zhong, Cheong-Meng Chong
Oxyimperatorin attenuates LPS-induced microglial activation in vitro and in vivo via suppressing NF-κB p65 signaling.
Biomed Pharmacother: 2024, 173;116379
[PubMed:38452656] [WorldCat.org] [DOI] (I p)

Yujie Li, Xiaoling Cui, Wenxia An, Chengyu Li, Song Zhang, Mengji Cao, Caixia Yang
The complete genome sequence of a putative novel cytorhabdovirus identified in Chelidonium majus in China.
Arch Virol: 2024, 169(3);56
[PubMed:38386128] [WorldCat.org] [DOI] (I e)

Wenhui Liu, Kexin Li, Han Zhang, Yeling Li, Zhen Lin, Jing Xu, Yuanqiang Guo
An antitumor arabinan from Glehnia littoralis activates immunity and inhibits angiogenesis.
Int J Biol Macromol: 2024, 263(Pt 2);130242
[PubMed:38368974] [WorldCat.org] [DOI] (I p)

Rengasamy Balakrishnan, Yon-Suk Kim, Ga-Won Kim, Woo-Jung Kim, Sun-Mee Hong, Choong-Gon Kim, Dong-Kug Choi
Standardized extract of Glehnia Littoralis abrogates memory impairment and neuroinflammation by regulation of CREB/BDNF and NF-κB/MAPK signaling in scopolamine-induced amnesic mice model.
Biomed Pharmacother: 2023, 165;115106
[PubMed:37421783] [WorldCat.org] [DOI] (I p)

Shiyang Li, Nan Xu, Qinqin Fang, Xuemei Cheng, Jiamei Chen, Ping Liu, Li Li, Changhong Wang, Wei Liu
Glehnia littoralis Fr. Schmidtex Miq.: A systematic review on ethnopharmacology, chemical composition, pharmacology and quality control.
J Ethnopharmacol: 2023, 317;116831
[PubMed:37369334] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects