Gentiana dahurica

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Nomenclature

Other Names:

Historical Use of Gentiana dahurica

Gentiana dahurica in Traditional Chinese Medicine

Background

Xiqinjiao Î÷ÇØÜ´ Zuoqinjiao ×óÇØÜ´ Chinese Name (pinyin): Qinjiao

Chinese Name  :

Common Name  :Large-Leaf Gentian Root

Specific Name  : Radix gentianae macrophyllae

Scientific Name:
Collection  : The drug is collected in spring and autumn, removed from soil, Qinjiao and Mahuajiao are soften in the sun either pile up until the drug becomes reddish yellow or greyish yellow `on the surface, spread out and dried in the sun or sundried directly after collecting; as for "Xiaoqinjiao" the black bark is rubbed off while fresh and dried in the sun.

Description  : Qinjiao Subcylindrical, the upper part thick and the lower part thin, twisted, 10 - 30 cm long, 1 - 3 cm in diameter. Externally yellowish brown or greyish yellow with longitudinal or twisted wrinkles. Remains of stem bases and fibrous pericladium occurring at the apex. Texture hard and fragile, easily broken, fracture soft, bark yellow or brownish yellow, wood yellow. Odour characteristic, taste bitter and slightly astringent.Mahuajiao: Subconical, frequently expanded by some small roots gathered up to 7 cm in diameter. Externally dark brown, rough with fissures showing reticulated pits. Texture lax and fragile, easily broken, fracture frequently rotten-wood-shaped.Xiaqinjiao: Sub conical or subcylindrical, 8 - 15 cm long. ).2 - 1 cm in diameter. Externally brownish yellow. Main root frequently 1, having fibrous pericladia on the remains of the stem bases, often branched at the lower part, fracture yellowish white.

Identification  : 1.Macerate 2g of the coarse powder in 30 ml of chloroform-methanol-concentrated ammonia TS (75:25:5) for 2 hours and filter. Concentrate the filtrate on the water bath to about 1 ml. Add 2 ml of hydrochloric acid solution (1 mol/L) and continue to evaporate the chloroform, cool and filter. Transfer the filtrate to two test tubes, to 1 tube add mercuric potassium iodide TS, a pale yellowish white precipitate is produced, to another tube add potassium iodobismuthate TS, a brownish red precipitate is produced.2.Examine the fracture under ultra violet light (365 nm), a yellowish white or golden yellow fluorescence is shown.Extractives: Carry out the hot maceration method as described under the determination of ethanol-soluble extractives (Appendix X A) using ethanol as the solvent, not less than 24.0%.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dried in the sun.

Action  : To relieve rheumatic conditions, and to remove damp-heat.

Indication  : rheumatic or rheumatoid arthritis with muscular contracture and severe joint pain; daily recurring afternoon fever, fever in infants with malnutrition

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Gentiana dahurica

Patent Medicines and Medicines with Multiple Ingredients that include Gentiana dahurica

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Gentiana dahurica in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Zeyun Li, Yue Du, Yongliang Yuan, Xiaojian Zhang, Zhengtao Wang, Xin Tian
Integrated quality evaluation strategy for multi-species resourced herb medicine of Qinjiao by metabolomics analysis and genetic comparation.
Chin Med: 2020, 15;16
[PubMed:32071612] [WorldCat.org] [DOI] (P e)

Karolina Tomiczak, Anna Mikuła, Agnieszka Niedziela, Anna Wójcik-Lewandowska, Lucyna Domżalska, Jan J Rybczyński
Somatic Embryogenesis in the Family Gentianaceae and Its Biotechnological Application.
Front Plant Sci: 2019, 10;762
[PubMed:31244878] [WorldCat.org] [DOI] (P e)

Qin-Zheng Hou, Xia Pang, Yu-Pei Wang, Kun Sun, Ling-Yun Jia, Shi-Hu Zhang, Qiao-Xia Li
Urbanization threaten the pollination of Gentiana dahurica.
Sci Rep: 2019, 9(1);583
[PubMed:30679533] [WorldCat.org] [DOI] (I e)

Tao Zhou, Jian Wang, Yun Jia, Wenli Li, Fusheng Xu, Xumei Wang
##Title##
Int J Mol Sci: 2018, 19(7);
[PubMed:29976857] [WorldCat.org] [DOI] (I e)

Liang-hong Ni, Zhi-li Zhao, Bo Xiong, Dorje Gaawe, Ma Mi
[A strategy for identifying six species of Sect.Cruciata(Gentiana) in Gansu using DNA barcode sequences].
Yao Xue Xue Bao: 2016, 51(5);821-7
[PubMed:29878733] [WorldCat.org] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects