Gentiana crassicaulis
Contents
Nomenclature
Other Names:
Historical Use of Gentiana crassicaulis
Gentiana crassicaulis in Traditional Chinese Medicine
Background
Xiqinjiao Î÷ÇØÜ´
Zuoqinjiao ×óÇØÜ´
Chinese Name (pinyin): Qinjiao
Chinese Name :
Common Name :Large-Leaf Gentian Root
Specific Name : Radix gentianae macrophyllae
Scientific Name:
Collection : The drug is collected in spring and autumn, removed from soil, Qinjiao and Mahuajiao are soften in the sun either pile up until the drug becomes reddish yellow or greyish yellow `on the surface, spread out and dried in the sun or sundried directly after collecting; as for "Xiaoqinjiao" the black bark is rubbed off while fresh and dried in the sun.
Description : Qinjiao Subcylindrical, the upper part thick and the lower part thin, twisted, 10 - 30 cm long, 1 - 3 cm in diameter. Externally yellowish brown or greyish yellow with longitudinal or twisted wrinkles. Remains of stem bases and fibrous pericladium occurring at the apex. Texture hard and fragile, easily broken, fracture soft, bark yellow or brownish yellow, wood yellow. Odour characteristic, taste bitter and slightly astringent.Mahuajiao: Subconical, frequently expanded by some small roots gathered up to 7 cm in diameter. Externally dark brown, rough with fissures showing reticulated pits. Texture lax and fragile, easily broken, fracture frequently rotten-wood-shaped.Xiaqinjiao: Sub conical or subcylindrical, 8 - 15 cm long. ).2 - 1 cm in diameter. Externally brownish yellow. Main root frequently 1, having fibrous pericladia on the remains of the stem bases, often branched at the lower part, fracture yellowish white.
Identification : 1.Macerate 2g of the coarse powder in 30 ml of chloroform-methanol-concentrated ammonia TS (75:25:5) for 2 hours and filter. Concentrate the filtrate on the water bath to about 1 ml. Add 2 ml of hydrochloric acid solution (1 mol/L) and continue to evaporate the chloroform, cool and filter. Transfer the filtrate to two test tubes, to 1 tube add mercuric potassium iodide TS, a pale yellowish white precipitate is produced, to another tube add potassium iodobismuthate TS, a brownish red precipitate is produced.2.Examine the fracture under ultra violet light (365 nm), a yellowish white or golden yellow fluorescence is shown.Extractives: Carry out the hot maceration method as described under the determination of ethanol-soluble extractives (Appendix X A) using ethanol as the solvent, not less than 24.0%.
Processing : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dried in the sun.
Action : To relieve rheumatic conditions, and to remove damp-heat.
Indication : rheumatic or rheumatoid arthritis with muscular contracture and severe joint pain; daily recurring afternoon fever, fever in infants with malnutrition
Precautions :
Dosage : 3 to 9 g.
Storage : Preserve in a ventilated and dry place.
Nomenclature
Other Names:
Historical Use of Gentiana crassicaulis
Gentiana crassicaulis in Traditional Chinese Medicine
Background
Xiqinjiao Î÷ÇØÜ´
Zuoqinjiao ×óÇØÜ´
Chinese Name (pinyin): Qinjiao
Chinese Name :
Common Name :Large-Leaf Gentian Root
Specific Name : Radix gentianae macrophyllae
Scientific Name:
Collection : The drug is collected in spring and autumn, removed from soil, Qinjiao and Mahuajiao are soften in the sun either pile up until the drug becomes reddish yellow or greyish yellow `on the surface, spread out and dried in the sun or sundried directly after collecting; as for "Xiaoqinjiao" the black bark is rubbed off while fresh and dried in the sun.
Description : Qinjiao Subcylindrical, the upper part thick and the lower part thin, twisted, 10 - 30 cm long, 1 - 3 cm in diameter. Externally yellowish brown or greyish yellow with longitudinal or twisted wrinkles. Remains of stem bases and fibrous pericladium occurring at the apex. Texture hard and fragile, easily broken, fracture soft, bark yellow or brownish yellow, wood yellow. Odour characteristic, taste bitter and slightly astringent.Mahuajiao: Subconical, frequently expanded by some small roots gathered up to 7 cm in diameter. Externally dark brown, rough with fissures showing reticulated pits. Texture lax and fragile, easily broken, fracture frequently rotten-wood-shaped.Xiaqinjiao: Sub conical or subcylindrical, 8 - 15 cm long. ).2 - 1 cm in diameter. Externally brownish yellow. Main root frequently 1, having fibrous pericladia on the remains of the stem bases, often branched at the lower part, fracture yellowish white.
Identification : 1.Macerate 2g of the coarse powder in 30 ml of chloroform-methanol-concentrated ammonia TS (75:25:5) for 2 hours and filter. Concentrate the filtrate on the water bath to about 1 ml. Add 2 ml of hydrochloric acid solution (1 mol/L) and continue to evaporate the chloroform, cool and filter. Transfer the filtrate to two test tubes, to 1 tube add mercuric potassium iodide TS, a pale yellowish white precipitate is produced, to another tube add potassium iodobismuthate TS, a brownish red precipitate is produced.2.Examine the fracture under ultra violet light (365 nm), a yellowish white or golden yellow fluorescence is shown.Extractives: Carry out the hot maceration method as described under the determination of ethanol-soluble extractives (Appendix X A) using ethanol as the solvent, not less than 24.0%.
Processing : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dried in the sun.
Action : To relieve rheumatic conditions, and to remove damp-heat.
Indication : rheumatic or rheumatoid arthritis with muscular contracture and severe joint pain; daily recurring afternoon fever, fever in infants with malnutrition
Precautions :
Dosage : 3 to 9 g.
Storage : Preserve in a ventilated and dry place.
Synonymns for Gentiana crassicaulis
Patent Medicines and Medicines with Multiple Ingredients that include Gentiana crassicaulis
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Gentiana crassicaulis in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Qiao Gao, Li-Xiang Zhou, Rong Huang, Shu-Xian Zhang, Guang Chen
Five New Glycoside Constituents from the Roots of Gentiana crassicaulis Duthie ex Burk.
Chem Biodivers: 2023, 20(8);e202300841
[PubMed:37462846]
[WorldCat.org]
[DOI]
(I p)
Jiangyi Luo, Hanwen Yuan, Ling Liang, Qinling Xie, Sai Jiang, Yangfen Fu, Shenghuang Chen, Wei Wang
An integrated strategy for quality control of the multi-origins herb medicine of Gentianae Macrophyllae Radix based on UPLC-Orbitrap-MS/MS and HPLC-DAD.
RSC Adv: 2023, 13(13);8847-8862
[PubMed:36936846]
[WorldCat.org]
[DOI]
(I e)
Kelsang Gyab Ala, Zhili Zhao, Lianghong Ni, Zhengtao Wang
Comparative analysis of mitochondrial genomes of two alpine medicinal plants of Gentiana (Gentianaceae).
PLoS One: 2023, 18(1);e0281134
[PubMed:36701356]
[WorldCat.org]
[DOI]
(I e)
Lianghong Ni, Weitao Li, Zhili Zhao, Dorje Gaawe, Tonghua Liu
##Title##
Ecol Evol: 2022, 12(3);e8703
[PubMed:35342601]
[WorldCat.org]
[DOI]
(P e)
Hai-Su Hu, De-Quan Zhang
[DNA super-barcoding of several medicinal species in Gentiana from Yunnan province].
Zhongguo Zhong Yao Za Zhi: 2021, 46(20);5260-5269
[PubMed:34738428]
[WorldCat.org]
[DOI]
(P p)
