Fritillaria unibracteata

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Nomenclature

Other Names:

Historical Use of Fritillaria unibracteata

Fritillaria unibracteata in Traditional Chinese Medicine

Background

Chuanbei ´¨±´ Chinese Name (pinyin): Chuanbeimu

Chinese Name  :

Common Name  :Sichuan Fritillary Bulb

Specific Name  : Bulbus Fritillariae Cirrhosae

Scientific Name:
Collection  : The drug is collected in summer and autumn or when the snow melts, remove from fibrous root, coarse bark and soil, dried in the sun or at a lower temperature.

Description  : Songbei subconical or subspherical, 0.3-0.8cm high, 0.3-0.9cm in diameter, externally whitish. The outer scale leaves 2, varying considerably in size with the large scale closely embracing the small one, the uncovered part appearing crescent commonly known as "Huaizhong Baoyue" (holding the moon in the arms), apex closed with subcylindrical and slightly tapering buds and 1-2 small scales inside; apex obtuse or slightly acute, base even and slightly concave with greyish brown disk at the central part, remains of the fibrous roots occaasionally found. Texture: hard and fragile, fracture white, starchy, odor: slight, taste: slightly bitter.Qingbei: Nearly oblate, 0.4-1.4cm high, 0.4-1.6cm in diameter, outer scales leaves 2, almost uniform in size, embraced. Apex open with buds and 2-3 small scales inside and slender cylindrical remains of a stem.Lubei: Long conical, 0.7-2.5cm high, 0.5-2.5cm in diameter, externally whitish or pale brownish-yellow, some brown-maculate. Outer scales leaves 2, almost uniform in size. Apex open and somewhat tapering, base slightly acute or relatively obtuse.

Identification  : Powder, whitishSongbei and Qingbei: Starch granules fairly abundant, broadly ovoid, long spheroidal or irregularly spheroidal, some with uneven or slightly branch-like edges. 5-64µm in diameter, hilum short slit-shape, [pointed, V-shape or U shape and faint striations visible. Epidermal cells subrectangular, anticlinal walls sinous, rounded or oblate anomocytic stomata occasionally found. Spiral vessels 5-26µm in diameter.Lubei: Starch granules broadly ovoid, conchoidal, reniform or elipsiodal up to 60µm in diameter, hilum, V shaped,stellate or pointed, striation distinct, spiral and reticulate vessels even up to 64µm in diameter.

Processing  :

Action  : To remove heat, moisten the lung, resolve phlegm and relieve cough.

Indication  :

Precautions  : Incompatible with Radix Aconiti and allied drugs.

Dosage  : 3 to 9 g; to be ground into powder and taken with water, 1 to 2 g a time.

Storage  : Preserve in a ventilated dry place, protected from moth.

Synonymns for Fritillaria unibracteata

Patent Medicines and Medicines with Multiple Ingredients that include Fritillaria unibracteata

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Fritillaria unibracteata in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Feng Pan, Dina H El-Kashef, Rainer Kalscheuer, Werner E G Müller, Jungho Lee, Michael Feldbrügge, Attila Mándi, Tibor Kurtán, Zhen Liu, Wei Wu, Peter Proksch
Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017.
Eur J Med Chem: 2020, 191;112159
[PubMed:32101782] [WorldCat.org] [DOI] (I p)

Cai-Xia Li, Ying-Ying Liu, Hai-Sheng Feng, Shi-Zhen Ma
##Title##
Food Sci Nutr: 2019, 7(11);3527-3537
[PubMed:31763003] [WorldCat.org] [DOI] (P e)

Feng Pan, Kai Hou, Dan-Dan Li, Tian-Jiao Su, Wei Wu
Exopolysaccharides from the fungal endophytic Fusarium sp. A14 isolated from Fritillaria unibracteata Hsiao et KC Hsia and their antioxidant and antiproliferation effects.
J. Biosci. Bioeng.: 2019, 127(2);231-240
[PubMed:30177486] [WorldCat.org] [DOI] (I p)

A B Cunningham, J A Brinckmann, S-J Pei, P Luo, U Schippmann, X Long, Y-F Bi
High altitude species, high profits: Can the trade in wild harvested Fritillaria cirrhosa (Liliaceae) be sustained?
J Ethnopharmacol: 2018, 223;142-151
[PubMed:29751123] [WorldCat.org] [DOI] (I p)

Feng Pan, Tian-Jiao Su, Yang Liu, Kai Hou, Chen Chen, Wei Wu
Extraction, purification and antioxidation of a polysaccharide from Fritillaria unibracteata var. wabuensis.
Int. J. Biol. Macromol.: 2018, 112;1073-1083
[PubMed:29447973] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects