Fritillaria cirrhosa

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Nomenclature

Other Names:

Historical Use of Fritillaria cirrhosa

Fritillaria cirrhosa in Traditional Chinese Medicine

Background

Chuanbei ´¨±´ Chinese Name (pinyin): Chuanbeimu

Chinese Name  :

Common Name  :Sichuan Fritillary Bulb

Specific Name  : Bulbus Fritillariae Cirrhosae

Scientific Name:
Collection  : The drug is collected in summer and autumn or when the snow melts, remove from fibrous root, coarse bark and soil, dried in the sun or at a lower temperature.

Description  : Songbei subconical or subspherical, 0.3-0.8cm high, 0.3-0.9cm in diameter, externally whitish. The outer scale leaves 2, varying considerably in size with the large scale closely embracing the small one, the uncovered part appearing crescent commonly known as "Huaizhong Baoyue" (holding the moon in the arms), apex closed with subcylindrical and slightly tapering buds and 1-2 small scales inside; apex obtuse or slightly acute, base even and slightly concave with greyish brown disk at the central part, remains of the fibrous roots occaasionally found. Texture: hard and fragile, fracture white, starchy, odor: slight, taste: slightly bitter.Qingbei: Nearly oblate, 0.4-1.4cm high, 0.4-1.6cm in diameter, outer scales leaves 2, almost uniform in size, embraced. Apex open with buds and 2-3 small scales inside and slender cylindrical remains of a stem.Lubei: Long conical, 0.7-2.5cm high, 0.5-2.5cm in diameter, externally whitish or pale brownish-yellow, some brown-maculate. Outer scales leaves 2, almost uniform in size. Apex open and somewhat tapering, base slightly acute or relatively obtuse.

Identification  : Powder, whitishSongbei and Qingbei: Starch granules fairly abundant, broadly ovoid, long spheroidal or irregularly spheroidal, some with uneven or slightly branch-like edges. 5-64µm in diameter, hilum short slit-shape, [pointed, V-shape or U shape and faint striations visible. Epidermal cells subrectangular, anticlinal walls sinous, rounded or oblate anomocytic stomata occasionally found. Spiral vessels 5-26µm in diameter.Lubei: Starch granules broadly ovoid, conchoidal, reniform or elipsiodal up to 60µm in diameter, hilum, V shaped,stellate or pointed, striation distinct, spiral and reticulate vessels even up to 64µm in diameter.

Processing  :

Action  : To remove heat, moisten the lung, resolve phlegm and relieve cough.

Indication  :

Precautions  : Incompatible with Radix Aconiti and allied drugs.

Dosage  : 3 to 9 g; to be ground into powder and taken with water, 1 to 2 g a time.

Storage  : Preserve in a ventilated dry place, protected from moth.

Synonymns for Fritillaria cirrhosa

Patent Medicines and Medicines with Multiple Ingredients that include Fritillaria cirrhosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Fritillaria cirrhosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Qi Chen, Xiaobo Wu, Dequan Zhang
Comparison of the abilities of universal, super, and specific DNA barcodes to discriminate among the original species of Fritillariae cirrhosae bulbus and its adulterants.
PLoS ONE: 2020, 15(2);e0229181
[PubMed:32053689] [WorldCat.org] [DOI] (I e)

Simei Liu, Tiechui Yang, Tse Wai Ming, Tse Kathy Wai Gaun, Ting Zhou, Shu Wang, Bengui Ye
Isosteroid alkaloids from Fritillaria cirrhosa bulbus as inhibitors of cigarette smoke-induced oxidative stress.
Fitoterapia: 2020, 140;104434
[PubMed:31760067] [WorldCat.org] [DOI] (I p)

Qing Lin, Mengke Qu, Hirak K Patra, Shanshan He, Luyao Wang, Xun Hu, Linyu Xiao, Yu Fu, Tao Gong, Qin He, Ling Zhang, Xun Sun, Zhirong Zhang
Mechanistic and therapeutic study of novel anti-tumor function of natural compound imperialine for treating non-small cell lung cancer.
J Ethnopharmacol: 2020, 247;112283
[PubMed:31605736] [WorldCat.org] [DOI] (I p)

Qi Chen, Xiaobo Wu, Dequan Zhang
##Title##
PeerJ: 2019, 7;e7480
[PubMed:31497389] [WorldCat.org] [DOI] (P e)

Shuanghu Wang, Zhiguang Zhang, Zheng Yu, Cheng Han, Xianqin Wang
Pharmacokinetic Study of Delavinone in Mice after Intravenous and Oral Administration by UPLC-MS/MS.
Biomed Res Int: 2019, 2019;3163218
[PubMed:31016188] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects