Ferula sinkiangensis

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Nomenclature

Other Names:

Historical Use of Ferula sinkiangensis

Ferula sinkiangensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Awei

Chinese Name  :

Common Name  :Chinese Asafetida

Specific Name  : Resina ferulae

Scientific Name:
Collection  : The stem is incised from the upper part to the lower part at the flowering and fruiting stage in the end of spring and early summer. The exuding emulsive resin is collected and dried in the shade.

Description  : Irregular lumps or resinous substance, color varying in intensity, externally waxy yellow to brownish yellow. Lumps light, texture waxy, fracture somewhat pored, freshly cut surface pale, gradually darken on storage. Resinous substance viscid, greyish white, odor strongly and lastingly characteristic and alliaceous, taste pungent with a burning sensation on chewing.

Identification  : 1.Dissolve small quantity in a few drops of sulfuric acid, a yellowish brown to reddish brown color is produced. Add ammonia TS to make the solution alkaline and examine under ultra violet light (365 nm) a light blue fluorescence is produced.2.To small quantity add 0.5 ml of hydrochloric acid and boil, a pale yellowish brown or pale purplish red colour is produced. Add a small quantity of phloroglucinol, the color becomes pale, continue to boil, a purplish brown color is produced.3.Add 1 drop of nitric acid on the freshly cut surface, a green color is produced which changes gradually to yellowish brown color.4.Place 0.2 g in a 10 ml graduated test tube, add dehydrated ethanol to volume, grind, macerate for 30 minutes and filter. Transfer 0.2 ml of the filtrate to 50 ml volumetric flask, add dehydrated ethanol to volume and mix well. The light absorption of the resulting solution exhibit a maximum at 323 nm (Appendix V A). Total ash: Not more than 7.0% (Appendix V A)Assay: Carry out the method for determination of volatile oil (Appendix ll D), using 5 - 10g. It contains not less than 10.0% of volatile oil.

Processing  :

Action  : To remove food stagnancy, to disintegrate masses.

Indication  : stagnationn of undigested meat, mass in the abdomen due to blood stasis, abdominal pain due to intestinal parasitosis

Precautions  : Contraindicated in pregnancy.

Dosage  : 1 to 1.5 g.

Storage  : Preserve in well closed containers, stored in a cool and dry place.

Synonymns for Ferula sinkiangensis

Patent Medicines and Medicines with Multiple Ingredients that include Ferula sinkiangensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Ferula sinkiangensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Lijing Zhang, Xiaobo Sun, Jianyong Si, Guangzhi Li, Li Cao
Umbelliprenin isolated from Ferula sinkiangensis inhibits tumor growth and migration through the disturbance of Wnt signaling pathway in gastric cancer.
PLoS ONE: 2019, 14(7);e0207169
[PubMed:31260453] [WorldCat.org] [DOI] (I e)

Yong-Hong Liu, Bao-Zhu Fang, Zhou-Yan Dong, Li Li, Osama Abdalla Abdelshafy Mohamad, Yong-Guang Zhang, Dilfuza Egamberdieva, Min Xiao, Wen-Jun Li
Croceibacterium gen. nov., with description of Croceibacterium ferulae sp. nov., an endophytic bacterium isolated from Ferula sinkiangensis K. M. Shen and reclassification of Porphyrobacter mercurialis as Croceibacterium mercuriale comb. nov.
Int. J. Syst. Evol. Microbiol.: 2019, 69(8);2547-2554
[PubMed:31215860] [WorldCat.org] [DOI] (I p)

Tao Zhang, Zhongke Wang, Xinhua Lv, Yang Li, Li Zhuang
High-throughput sequencing reveals the diversity and community structure of rhizosphere fungi of Ferula Sinkiangensis at different soil depths.
Sci Rep: 2019, 9(1);6558
[PubMed:31024051] [WorldCat.org] [DOI] (I e)

Tingting Liu, Liping Wang, Lan Zhang, Hongyun Jiang, Yanning Zhang, Liangang Mao
Insecticidal, cytotoxic and anti-phytopathogenic fungal activities of chemical constituents from the aerial parts of Ferula sinkiangensis.
Nat. Prod. Res.: 2018;1-7
[PubMed:30417676] [WorldCat.org] [DOI] (I a)

Huan Liu, Cai-Yun Zhao, Wen Zhang, Yi Zhang, Jia Nie
[Study on medication laws of Tibetan medicine in treatment of plateau disease based on data mining technology].
Zhongguo Zhong Yao Za Zhi: 2018, 43(8);1726-1731
[PubMed:29751723] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects