Euphorbia pekinensis

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Nomenclature

Other Names:

Historical Use of Euphorbia pekinensis

Euphorbia pekinensis in Traditional Chinese Medicine

Background

Hongya Daji ºìÑ¿´óêª Chinese Name (pinyin): Daji

Chinese Name  :

Common Name  :Peking Spurge Root

Specific Name  : Herba cirsii japonici/ Radix cirsii japonici

Scientific Name:
Collection  :

Description  :

Identification  :

Processing  :

Action  : To arrest bleeding by reducing heat in the blood, to remove blood stasis, and to promote the subsidence of swelling.

Indication  :

Precautions  :

Dosage  : 9 to 15 g; for external use, appropriate quantity of the fresh herb to be pounded into paste and applied topically.

Storage  : Preserve in a ventilated and dry place.

Tcm p52 0008.jpg
P287 1.jpg

Nomenclature

Other Names:

Historical Use of Euphorbia pekinensis

Euphorbia pekinensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Jingdaji

Chinese Name  :

Common Name  :Peking Euphorbia Root

Specific Name  : Radix euphorbiae pekinensis

Scientific Name:
Collection  : The drug is collected in autumn and winter, wash clean and dried in the sun.

Description  : Irregularly long conical, slightly curved, usually branched, 10 - 20 cm long, 1.5 - 4 cm in diameter. Externally greyish brown or brown, rough, exhibiting longitudinal wrinkles, transverse lenticels and branch root scars. Apex slightly expanded with numerous stem bases and bud scars. Texture hard, uneasily broken, fracture whitish or pale yellow and fibrous. Odour slight, taste slightly bitter and astringent.

Identification  : 1.Powder: Pale yellow, simple starch granules subspheroid or ovoid. 3 - 15 µm in diameter, hilum pointed or slit shaped. Compound granules of 2 - 3 components. Cluster of calcium oxalate 19 - 40 µm in diameter. Bordered pitted and reticulate vessels more commonly found, 26 - 50 µm in diameter. Fibres individual or in bundles, walls relatively thick and non lignified. Non-articulate laticiferous tubes mostly broken containing yellow minute latex granules.2.To a slice of the drug add 1 drop of each of the glacial acetic acid and sulfuric acid, observe under a microscope, a red colour is produced at the laticiferous tubes of phloem which gradually disappears within 5 minutes, to another slice, add potassium hydroxide TS, a brownish yellow colour is produced.Processing: Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.Processed with vinegar: Boil as described under the method of boiling with vinegar (Appendix ll D) until vinegar is exhausted. Use 30 kg of vinegar per 100 kg of Radix Euphorbiae Pekinensis.

Action  : To cause drastirc purgation.

Indication  : anasarca, hydrothorax, ascites with dyspnea, constipation and oliguria

Precautions  : Contraindicated in pregnancy. Incompatible with Radix Glycyrrhizae.

Dosage  : 1.5 to 3 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Euphorbia pekinensis

Patent Medicines and Medicines with Multiple Ingredients that include Euphorbia pekinensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Euphorbia pekinensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Fang Yao, Dongjing Jiang, Fangfang Cheng, Weifeng Yao, Peidong Chen, Shuchen Guo, Yudan Cao, Li Zhang
Diterpene pekinenal from euphorbia pekinensis radix induced IEC-6 cells apoptosis mediated by mitochondria and death receptors.
Toxicol In Vitro: 2019, 57;1-8
[PubMed:30710624] [WorldCat.org] [DOI] (I p)

Zhenzhen Liu, Yan Zeng, Pengyi Hou
Metabolomic evaluation of Euphorbia pekinensis induced nephrotoxicity in rats.
Pharm Biol: 2018, 56(1);145-153
[PubMed:29421944] [WorldCat.org] [DOI] (I p)

Ik-Soo Lee, Seung-Hyun Jung, Jin Sook Kim
Polyphenols from Euphorbia pekinensis Inhibit AGEs Formation In Vitro and Vessel Dilation in Larval Zebrafish In Vivo.
Planta Med.: 2018, 84(3);176-181
[PubMed:29165729] [WorldCat.org] [DOI] (I p)

Hongli Yu, Lian Liu, Kuilong Wang, Hao Wu, Wei Wang, Xingde Zhang, Guojing Cui, Xiaobing Cui, Jianyu Huang
Upregulation of aquaporin 3 expression by diterpenoids in Euphorbia pekinensis is associated with activation of the NF-κB signaling pathway in the co-culture system of HT-29 and RAW 264.7 cells.
Biochimie: 2018, 144;153-159
[PubMed:29129744] [WorldCat.org] [DOI] (I p)

Kai-Cheng Zhang, Yu-Dan Cao, Fang Yao, Li Zhang, An-Wei Ding
[Acute toxicity of Euphorbiae Pekinensis Radix and vinegar-processing Euphorbiae Pekinensis Radix on zebrafish embryo].
Zhongguo Zhong Yao Za Zhi: 2017, 42(12);2291-2297
[PubMed:28822182] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects