Euphorbia humifusa

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Nomenclature

Other Names:

Historical Use of Euphorbia humifusa

Euphorbia humifusa in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Dijincao

Chinese Name  :

Common Name  :Creeping Euphorbia

Specific Name  : Herba euphorbiae humifusae

Scientific Name:
Collection  : The drug is collected in summer and autumn, removed from foreign matter and dried in the sun.

Description  : Herb of Euphorbia humifusa: Frequently crumpled and curved, roots thin, stems thin, furcate branched, externally purplish-red, glabrous or sparsely white furry, texture fragile, fracture yellowish white. Hollowed in the center. Leaves simple, opposite with pale red, short petioles or almost sessile, lamina mostly crumpled or fallen off when whole. Long elliptic 5 - 10mm long, 4 - 6mm wide, green or purplish red, frequently glabrous or sparsely furry, apex obtusely rounded, base oblique, margin serrulated or slightly sinuous. Cup shaped cyme axillary, small. Capsules triangular-spherical, externally smooth, seeds small, ovoid, brown, odorless, taste slightly astringent.Herb of Euphorbia maculata: Leaves with red spots on the upper surface, capsules sparsely white furry.

Identification  : Powder greenish brown, outer walls of the leaves epidermal cells papillary. Surrounding cells of the fine vein ends in mesophyll arranged radiately in circles. Non-glandular hairs 3 - 8 celled, about 14µm in diameter mostly broken. Non-articulate laticiferous tubes containing fine lamellar starch granules.

Processing  : Eliminate foreign matter, spray with water, soften briefly, cut into sections and dry in the sun.

Action  : To remove toxic heat and to arrest bleeding by reducing heat in blood.

Indication  : dysentery colitis; hemoptysis; hematuria; hemotchezia, abnormal uterine bleeding; boils, carbuncles

Precautions  :

Dosage  : 9 to 20 g; or 30 to 60 g of the fresh herb; appropriate quantity for external use.

Storage  : Preserve in a ventilated and dry place.

P159 2.jpg

Nomenclature

Other Names:

Historical Use of Euphorbia humifusa

Euphorbia humifusa in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Dijincao

Chinese Name  :

Common Name  :Creeping Euphorbia

Specific Name  : Herba euphorbiae humifusae

Scientific Name:
Collection  : The drug is collected in summer and autumn, removed from foreign matter and dried in the sun.

Description  : Herb of Euphorbia humifusa: Frequently crumpled and curved, roots thin, stems thin, furcate branched, externally purplish-red, glabrous or sparsely white furry, texture fragile, fracture yellowish white. Hollowed in the center. Leaves simple, opposite with pale red, short petioles or almost sessile, lamina mostly crumpled or fallen off when whole. Long elliptic 5 - 10mm long, 4 - 6mm wide, green or purplish red, frequently glabrous or sparsely furry, apex obtusely rounded, base oblique, margin serrulated or slightly sinuous. Cup shaped cyme axillary, small. Capsules triangular-spherical, externally smooth, seeds small, ovoid, brown, odorless, taste slightly astringent.Herb of Euphorbia maculata: Leaves with red spots on the upper surface, capsules sparsely white furry.

Identification  : Powder greenish brown, outer walls of the leaves epidermal cells papillary. Surrounding cells of the fine vein ends in mesophyll arranged radiately in circles. Non-glandular hairs 3 - 8 celled, about 14µm in diameter mostly broken. Non-articulate laticiferous tubes containing fine lamellar starch granules.

Processing  : Eliminate foreign matter, spray with water, soften briefly, cut into sections and dry in the sun.

Action  : To remove toxic heat and to arrest bleeding by reducing heat in blood.

Indication  : dysentery colitis; hemoptysis; hematuria; hemotchezia, abnormal uterine bleeding; boils, carbuncles

Precautions  :

Dosage  : 9 to 20 g; or 30 to 60 g of the fresh herb; appropriate quantity for external use.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Euphorbia humifusa

Patent Medicines and Medicines with Multiple Ingredients that include Euphorbia humifusa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Euphorbia humifusa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

T T Wang, Z Q Zhou, S Wang, X W Ji, B Wu, L Y Sun, J F Wen, D G Kang, H S Lee, K W Cho, S N Jin
Mechanisms of vasorelaxation induced by total flavonoids of Euphorbia humifusa in rat aorta.
J. Physiol. Pharmacol.: 2017, 68(4);619-628
[PubMed:29151079] [WorldCat.org] (I p)

Jin-Ni Hong, Wei-Wei Li, Lin-Lin Wang, Hao Guo, Yong Jiang, Yun-Jia Gao, Peng-Fei Tu, Xue-Mei Wang
Jiangtang decoction ameliorate diabetic nephropathy through the regulation of PI3K/Akt-mediated NF-κB pathways in KK-Ay mice.
Chin Med: 2017, 12;13
[PubMed:28529539] [WorldCat.org] [DOI] (P e)

Suyu Gao, Dejuan Sun, Guan Wang, Jin Zhang, Yingnan Jiang, Guoyu Li, Ke Zhang, Lei Wang, Jian Huang, Lixia Chen
Growth inhibitory effect of paratocarpin E, a prenylated chalcone isolated from Euphorbia humifusa Wild., by induction of autophagy and apoptosis in human breast cancer cells.
Bioorg. Chem.: 2016, 69;121-128
[PubMed:27814565] [WorldCat.org] [DOI] (I p)

Soon Young Shin, Chang Gun Kim, You Jung Jung, Yearam Jung, Hyeryoung Jung, Jihyun Im, Yoongho Lim, Young Han Lee
Euphorbia humifusa Willd exerts inhibition of breast cancer cell invasion and metastasis through inhibition of TNFα-induced MMP-9 expression.
BMC Complement Altern Med: 2016, 16(1);413
[PubMed:27776550] [WorldCat.org] [DOI] (I e)

So Young Chang, Ji Hoon Park, Young Ho Kim, Jong Seong Kang, Ji-Young Min
A natural component from Euphorbia humifusa Willd displays novel, broad-spectrum anti-influenza activity by blocking nuclear export of viral ribonucleoprotein.
Biochem. Biophys. Res. Commun.: 2016, 471(2);282-9
[PubMed:26850850] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects