Descurainia sophia

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P438 2.jpg
P438 1.jpg


Other Names:

Historical Use of Descurainia sophia

Descurainia sophia in Traditional Chinese Medicine


Kutingli ¿àÝãÜ Tiantingli ÌðÝãÜ Chinese Name (pinyin): Tinglizi

Chinese Name  :

Common Name  :Lepidium Seed

Specific Name  : Semen lepidii/ Semen descurainiae

Scientific Name:
Collection  : The fruit is collected when the fruit is ripe, dried in the sun and the seed is gathered and remove from foreign matter.

Description  : Seed of Lepidium Apetalum. Flattened ovoid, 1 - 1.5 mm long, 0.5 - 1mm wide. Externally brown or reddish brown, somewhat lustrous with 2 longitudinal furrows, one of them relatively distinct. One end obtuse, the other acute and slightly concave, almost white, hilum situated at the concave end. Odorless, taste slightly pungent and relatively viscous.Seed of Descurainia Sophia: Oblong somewhat flattened, about 1 mm long, 0.5 mm wide. One end obtuse, the other end slightly concave or relatively truncate. Taste slightly pungent and bitter. Somewhat viscous.

Identification  : 1.Macerate a small quantity of the drug in water, observe under magnifier, the transparent mucilage layer of Seed of Lipidium apetalum is relatively thick occurred in more than ½ of the width of seed. The transparent mucilage of Seed Descurainia sophia is thin and occurs in less than about 1/5 of the width of the seed.2.Seed of Lepidium apetalum. Powder: yellowish brown. Epidermal cells of tetsa consisting of mucilage cells, rectangular in section view, thickened inner walls, extending outwards to cellulose column, 24 - 34µm long, obtuse rounded, oblique or truncate at the apex,, mucilage striations visible in periphery. Inner epidermal cells of testa yellow, polygonal, sub-square, sometimes long polygonal in surface view, 15 - 42µm in diameter, walls 5 - 8µm thick.Seed of Descurainia sophia: Outer epidermal cells of testa sub-square in section view, cellulose column short. 8 - 18µm long, inner epidermal cells of testa polygonal in surface view.Swelling capacity: Weigh about 0.6g of the drug, carry out the method for determination of swelling capacity (Appendix lX O), not less than 12 for Semen Lepidii and not less than 3 for Semen Descurainiae.

Processing  : Eliminate foreign matters.Semen Lepidii or Semen Descurainiae (stir fried): Stir fry as described under the method for simple stir frying (Appendix ll D) until it cracks.

Action  : To quench fire in the lung, to relieve dyspnea, and to cause diuresis.

Indication  : dyspnea or orthopnea, cough with profuse expectoration and fullness sensation in the chest, accompanied by hydrothorax, ascites and oliguria; edema in pulmonary heart disease

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a dry place.

Synonymns for Descurainia sophia

Patent Medicines and Medicines with Multiple Ingredients that include Descurainia sophia

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Descurainia sophia in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Eun-Sang Cho, Sarah Shin, You Jin Lee, No Soo Kim, Jinhee Kim, Seok-Jong Lee, Hwa-Young Son, Woo-Joo Lee, Ok-Sun Bang
Toxicological assessments of an ethanol extract complex of Descurainia sophia and Peucedanum praeruptorum: Subacute oral toxicity and genotoxicity studies.
J Appl Toxicol: 2020;
[PubMed:32084673] [] [DOI] (I a)

Ren-Yu Qu, Jing-Fang Yang, Qiong Chen, Cong-Wei Niu, Zhen Xi, Wen-Chao Yang, Guang-Fu Yang
Fragment-based discovery of flexible inhibitor targeting wild-type acetohydroxyacid synthase and P197L mutant.
Pest Manag. Sci.: 2020;
[PubMed:31943722] [] [DOI] (I a)

Nai-Chun Ting, Wen-Chung Huang, Li-Chen Chen, Sien-Hung Yang, Ming-Ling Kuo
Am. J. Chin. Med.: 2019, 47(7);1507-1522
[PubMed:31752525] [] [DOI] (I p)

Sung-Bae Kim, Yun-Soo Seo, Hyo Seon Kim, A Yeong Lee, Jin Mi Chun, Byeong Cheol Moon, Bo-In Kwon
Anti-asthmatic effects of lepidii seu Descurainiae Semen plant species in ovalbumin-induced asthmatic mice.
J Ethnopharmacol: 2019, 244;112083
[PubMed:31344479] [] [DOI] (I p)

Jiahui Gui, Meilin Zhu, Xiangjian Bai, Bohan Li, Meijia Gao, Hui Ma, Hongmei Li, Chengzhu Wu
Nan Fang Yi Ke Da Xue Xue Bao: 2019, 39(2);169-174
[PubMed:30890504] [] [DOI] (P p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects