Cyathula officinalis

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Nomenclature

Other Names:

Historical Use of Cyathula officinalis

Cyathula officinalis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Chuanniuxi

Chinese Name  :

Common Name  :Medicinal Cyathula root

Specific Name  : Radix cyathulae

Scientific Name:
Collection  : The drug is collected in autumn and winter, removed from root stock, rootlet and soil, baked or sun dried to half dryness. Piled up to be soften and then baked or sunned until dried completely.

Description  : Subcylindrical, somewhat twisted, slightly tapering downward or less branched, 30 - 60 cm long, 0.5 - 3 cm in diameter. Externally yellowsih brown with longitudinal wrinkles, rootlet scars and numerous transversely protruding lenticels. Texture tenacious, uneasily broken, fracture pale yellow or brownish yellow, showing dotted vascular bundles arranged in several concentric circles. Odour slight and taste sweet.

Identification  : Transverse section: Cork consisting of several layers of cells. Cortex narrow. Stele large, tertiary vascular bundles collateral, interruptedly arranged in 4 - 11 whorls, intrafascicular cambium at a ring at the inner side visible, vessels singly scattered in xylem, lignified, arranged radially. Wood fibres rather developed, sometimes tangentially elongated or arranged in an interrupted ring, vascular system usually separated into 2 - 9 strands of the center of root. Some sparsely scattered vessels elements visible. Parenchymatous cells containing sand crystal and prisms or callcium oxalate.Powder: Brown, sand crystal and prisms of calcium oxalate scattered or filled in parenchymatous cells. Bordered pitted vessels 10 - 80 µm in diameter, pits rounded or elongated transversely, alternative closely arranged, some vessel elements fusiform at the ends. Fibres slat shaped curved, tapering into the end, 8 - 25 µm in diameter, walls 3 - 5µm thick, pits simple oblique or V-shaped sometimes showing bordered pits, pit apertures crisscross, pit canals distinct, dense or sparse.Extractives: Carry out the cold extraction method as described under the determination of water-soluble extractives (Appendix X A), using the granules of the diameter less than 3 mm. Not less than 65.0%.

Processing  : Eliminate foreign matter and root stock, wash clean, soften thoroughly, cut into thin slices and dry. In rounded slices, 0.1 - 0.2 cm thick, 0.5 - 3 cm in diameter. Externally greyish yellow, cut surfaces pale yellow or brownish yellow. Numerous yellow dotted vascular bundles visible.Stir fried with wine: Stir fry as described under the method for stir frying with wine (Appendix ll D) to dryness.

Action  : To eliminate blood stasis and stimulate menstrual discharge, to allay arthralgia and ease the joint, and to relieve urinary disturbance.

Indication  : amenorrhea with mass formation in the lower abdomen, detention after birth, arthalgia with contracture of the muscles and restrained movement of the legs, hematuria, traumatic injuries

Precautions  : Contraindicated in pregnancy.

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a cool and dry place, protected from moisture.

Synonymns for Cyathula officinalis

Patent Medicines and Medicines with Multiple Ingredients that include Cyathula officinalis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Cyathula officinalis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Haibo Feng, Jing Fan, Lang Lin, Yunjie Liu, Dongkun Chai, Jie Yang
##Title##
Molecules: 2019, 24(22);
[PubMed:31731832] [WorldCat.org] [DOI] (I e)

Hu-Biao Meng, Yuan Yuan, Fu-Yan Liu, Chao Jiang, Yan Jin, Yu-Yang Zhao
[Allele-specific PCR to identification of Achyranthis Bidentatae Radix and Cyathulae Radix formula granules].
Zhongguo Zhong Yao Za Zhi: 2018, 43(5);945-951
[PubMed:29676092] [WorldCat.org] [DOI] (P p)

Ming-Yan Wu, Lan He, Jia-Li Chen, Guang Dong, Wu-Xue Cheng
[Predictive distribution and planting GAP of Cyathula officinalis in China based on 3S technology and MaxEnt modelling].
Zhongguo Zhong Yao Za Zhi: 2017, 42(22);4395-4401
[PubMed:29318841] [WorldCat.org] [DOI] (P p)

Jiajing Zhao, Yaohan Yue, Yun Xie, Liwen Liu, Fei Cao, Shurong Gao, Yingjue Wang
##Title##
Exp Ther Med: 2017, 14(6);5395-5400
[PubMed:29285068] [WorldCat.org] [DOI] (P p)

Yanmei Cao, Cuicui Gu, Fangli Zhao, Yuanlin Tang, Xiaobing Cui, Le Shi, Li Xu, Lian Yin
##Title##
Pharmacogn Mag: 2016, 13(52);693-701
[PubMed:29200735] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects