Croton tiglium

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P95 1.jpg

Nomenclature

Other Names:

Historical Use of Croton tiglium

Croton tiglium in Traditional Chinese Medicine

Background

Badoushuang °Í¶¹Ëª Jiaobadou ½¹°Í¶¹ Chinese Name (pinyin): Badou

Chinese Name  :

Common Name  :Croton Seed

Specific Name  : Fructus crotonis

Scientific Name:
Collection  : The drug is collected in autumn when ripe, piled up for 2 - 3 days, spread out and dried.

Description  : Ovoid, usually 3 ribbed, 1.8 - 2.2cm long, 1.4 - 2cm in diameter, externally greyish yellow or slightly deep with 6 longitudinal lines, apex truncate, base with a a fruit stalk scar. 3 loculi in the shell each containing 1 seed. Seed slightly flattened-elliptical. 1.2 - 1.5 cm long, 7 - 9mm in diameter. Externally brown or greyish brown with a pointed hilum and caruncle scar at one end, a slightly dented chalaza at the other end and a raphe between two ends, testa thin and brittle, tegmen white, membranous, kernels yellowish white, oily, odorless and taste pungent.

Identification  : Macerate about 0.5g of the coarse powder in 10 ml of ethel for 2 hours with constant shaking and filter. Evaporate the filtrate to dryness in a test tube, add 0.5 of saturated solution of hydroxylamine hydrochloric in methanol and 1 drop of thymolphthalein IS and saturated solution of potassium hydroxide in methanol until a blue color is produce then and excess of 4 drops, boil and cool. Adjust the pH value to 2 - 3 by adding dilute hydrochloric acid solution, add 3 drops of ferric chloride RS and 1ml of chloroform and shake, a purlpish red color is produce in the lower layer

Processing  : Remove the coats to take the kernels.

Action  : To cause cauterization by external use.

Indication  : malignant ulcer, scabies, wart

Precautions  :

Dosage  : Appropritae quantity to be ground into powder for topical application or pounded into paste and wrapped in a piece of gauze for rubbing onto the affected skin.

Storage  : Preserve in a cool and dry place.

P95 1.jpg

Nomenclature

Other Names:

Historical Use of Croton tiglium

Croton tiglium in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Badoushuang

Chinese Name  :

Common Name  :Defatted croton seed powder

Specific Name  : Semen crotonis pulveratum

Scientific Name:
Collection  : Defatted croton seed powder is a processed product of croton seed.

Description  : A pale yellow, lax powder, homgeneous in size, oily in appearance.

Identification  : Complies with the test for Identification described under Fructus Crotonis.Assay: Heat under reflux about 5g of the powder, accurately weighed in a Soxhlet's extractor with 100 ml ether for 6 - 8 hours to exhaust fatty oil. Transfer the extract to the evaporating dish dried to constant weight, remove the ether at a low temperature on a water bath. Dry the residue at 100ºC for 1 hour, cool and weigh accurately. It contains 18-20% of fatty oil.

Processing  : Treat the clean Croton Seed as described under the method for frost like powder (Appendix ll D) or pulverize the seed and determine its content of fatty oil, add sufficient starch to make the fatty oil contents in compliance with the requirement and mix well.

Action  : To cause drastic purgation, to relieve edema, and to soothe the throat.

Indication  : constipation and indigestion due to accumulation of cold; ascites and edema with oliguria and constipation; inflammation of the throat

Precautions  : Contraindicated in pregnancy. In compatible with Semen Pharbitidis.

Dosage  : 0.1 to 0.3 g; mostly used for making pills or powder.

Storage  : Preserve in a cool and dry place.

Synonymns for Croton tiglium

Patent Medicines and Medicines with Multiple Ingredients that include Croton tiglium

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Croton tiglium in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Zewdie Kassa, Zemede Asfaw, Sebsebe Demissew
An ethnobotanical study of medicinal plants in Sheka Zone of Southern Nations Nationalities and Peoples Regional State, Ethiopia.
J Ethnobiol Ethnomed: 2020, 16(1);7
[PubMed:32024539] [WorldCat.org] [DOI] (I e)

Daniela H Oliveira, Fernanda S S Sousa, Paloma T Birmann, Diego Alves, Raquel G Jacob, Lucielli Savegnago
Antinociceptive and anti-inflammatory effects of 4-(arylchalcogenyl)-1H-pyrazoles containing selenium or sulfur.
Pharmacol Rep: 2020, 72(1);36-46
[PubMed:32016854] [WorldCat.org] [DOI] (I p)

S Malathi, P S Pavithra, S Sridevi, Rama S Verma
Fabrication of nanopatterned PLGA films of Curcumin and TPGS for skin cancer.
Int J Pharm: 2020;119100
[PubMed:32014600] [WorldCat.org] [DOI] (I a)

Rong Wang, Run-Zhu Fan, Fu-Qiang Ni, Jun Sang, Xing-Lin Xie, Si-Yuan Luo, Gui-Hua Tang, Sheng Yin
##Title##
J. Nat. Prod.: 2020;
[PubMed:32003565] [WorldCat.org] [DOI] (I a)

Ethel A Wilhelm, Paola S Soares, Angélica S Reis, Anelise Barth, Barbara G Freitas, Ketlyn P Motta, Briana B Lemos, Ane G Vogt, Caren A R da Fonseca, Daniela R Araujo, Angelita M Barcellos, Gelson Perin, Cristiane Luchese
Se - [(2,2-Dimethyl-1,3-dioxolan-4-yl) methyl] 4-chlorobenzoselenolate reduces the nociceptive and edematogenic response by chemical noxious stimuli in mice: Implications of multi-target actions.
Pharmacol Rep: 2019, 71(6);1201-1209
[PubMed:32002867] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects