Crataegus pinnatifida var. major
Contents
Nomenclature
Other Names:
Historical Use of Crataegus pinnatifida var. major
Crataegus pinnatifida var. major in Traditional Chinese Medicine
Background
Chaoshanzha ³´É½é«
Jiaoshanzha ½¹É½é«
Shanzhatan ɽé«Ì¿
Shengshanzha Éúɽé«
Chinese Name (pinyin): Shanzha
Chinese Name :
Common Name :Hawthorn Fruit
Specific Name : Fructus crataegi
Scientific Name:
Collection : The drug is collected in autumn when ripe, cut into slices and dried.
Description : Rounded slices shrunken and uneven, 1 - 2.5cm in diameter, 2 - 4mm thick. Externally red, wrinkled with a small greyish white spots. Pulp dark yellow to pale brown. Transverse slices of the middle part showing 5 pale yellow kerns, mostly fallen off and loculi hollowed, some slices exhibiting a slender fruit stalk or remains of calyx. Odor slightly aromatic, taaste sour and slightly sweet.
Identification : Assay: Soak about 1g of the fine powder, accurately measured for 4 hours with occasional shaking and filter. Determine the water content of the powder (Appendix lX h, method 1) with another sample. To 25ml of the filtrate accurately measured. Add 50ml of the water, 2 drops of phenolphtalein IS, titrate with sodium hydroxide (0.1 mol/L) VS and calculate the content. Each ml of sodium hydroxide (0.1mol/L) VS is equivalent to 6.404 mg of C6H8O7. It contains not less than 5.0% of organic acid, calculated as citric acid (C6H8O7) on the dried basis.
Processing : Eliminate foreign matter and fllen kernels.Stir fried: Stir fry as describe under the method for simple stir frying (Appendix ll D) until darkens in colour.Charred: Stir fry as describe under the method for simple stir frying (Appendix ll D) until becomes burnt-brown externally.
Action : To stimulate digestion and promote the functional activivty of stomach, to improve the normal flow of qi and dissipate blood stasis.
Indication : stagnation of undigested meat with epigastric distension, diarrhea and abdominal pain; amenorrhea due to blood stasis, epigastric pain or abdominal colic after childbirth; hyperlipidemia
Precautions :
Dosage : 9 to 12 g.
Storage : Preserve in a ventilated and dry place, protected from moth.
Synonymns for Crataegus pinnatifida var. major
Patent Medicines and Medicines with Multiple Ingredients that include Crataegus pinnatifida var. major
Pharmaceutical Information
Chemical Constituents
Evidence or the Use of Crataegus pinnatifida var. major in the Treatment of Epilepesy
Basic Science
Animal Studies
Cohort, Case-Control and Non-Randomized Trials
Randomized Controlled Trials
Meta-Analysis
1st Five Results: pubmed search
Xufeng Bai, Shuwen Wang, Limei Shu, Qingyu Cao, Huiming Hu, Yanchen Zhu, Chen Chen
Hawthorn leaf flavonoids alleviate the deterioration of atherosclerosis by inhibiting SCAP-SREBP2-LDLR pathway through sPLA2-ⅡA signaling in macrophages in mice.
J Ethnopharmacol: 2024, 327;118006
[PubMed:38442806]
[WorldCat.org]
[DOI]
(I p)
Yunxia Cheng, Zhenying Liu, Bo Xu, Pingping Song, Zhimao Chao
##Title##
Curr Res Food Sci: 2023, 7;100616
[PubMed:37881336]
[WorldCat.org]
[DOI]
(I e)
Yan Wang, Ruixin Hao, Rongkun Guo, Huilan Nong, Yu Qin, Ningguang Dong
Integrative Analysis of Metabolome and Transcriptome Reveals Molecular Insight into Metabolomic Variations during Hawthorn Fruit Development.
Metabolites: 2023, 13(3);
[PubMed:36984863]
[WorldCat.org]
[DOI]
(P e)
Ruiyu Li, Fei Luan, Yunyan Zhao, Mengyao Wu, Yang Lu, Chengtian Tao, Lv Zhu, Chi Zhang, Li Wan
Crataegus pinnatifida: A botanical, ethnopharmacological, phytochemical, and pharmacological overview.
J Ethnopharmacol: 2023, 301;115819
[PubMed:36228891]
[WorldCat.org]
[DOI]
(I p)
Shi-Yao Zhang, Xiao-Lei Sun, Xing-Liang Yang, Peng-Liang Shi, Ling-Chuan Xu, Qing-Mei Guo
Botany, traditional uses, phytochemistry and pharmacological activity of Crataegus pinnatifida (Chinese hawthorn): a review.
J Pharm Pharmacol: 2022, 74(11);1507-1545
[PubMed:36179124]
[WorldCat.org]
[DOI]
(I p)