Crataegus pinnatifida var. major

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Nomenclature

Other Names:

Historical Use of Crataegus pinnatifida var. major

Crataegus pinnatifida var. major in Traditional Chinese Medicine

Background

Chaoshanzha ³´É½é« Jiaoshanzha ½¹É½é« Shanzhatan ɽé«Ì¿ Shengshanzha ÉúÉ½é« Chinese Name (pinyin): Shanzha

Chinese Name  :

Common Name  :Hawthorn Fruit

Specific Name  : Fructus crataegi

Scientific Name:
Collection  : The drug is collected in autumn when ripe, cut into slices and dried.

Description  : Rounded slices shrunken and uneven, 1 - 2.5cm in diameter, 2 - 4mm thick. Externally red, wrinkled with a small greyish white spots. Pulp dark yellow to pale brown. Transverse slices of the middle part showing 5 pale yellow kerns, mostly fallen off and loculi hollowed, some slices exhibiting a slender fruit stalk or remains of calyx. Odor slightly aromatic, taaste sour and slightly sweet.

Identification  : Assay: Soak about 1g of the fine powder, accurately measured for 4 hours with occasional shaking and filter. Determine the water content of the powder (Appendix lX h, method 1) with another sample. To 25ml of the filtrate accurately measured. Add 50ml of the water, 2 drops of phenolphtalein IS, titrate with sodium hydroxide (0.1 mol/L) VS and calculate the content. Each ml of sodium hydroxide (0.1mol/L) VS is equivalent to 6.404 mg of C6H8O7. It contains not less than 5.0% of organic acid, calculated as citric acid (C6H8O7) on the dried basis.

Processing  : Eliminate foreign matter and fllen kernels.Stir fried: Stir fry as describe under the method for simple stir frying (Appendix ll D) until darkens in colour.Charred: Stir fry as describe under the method for simple stir frying (Appendix ll D) until becomes burnt-brown externally.

Action  : To stimulate digestion and promote the functional activivty of stomach, to improve the normal flow of qi and dissipate blood stasis.

Indication  : stagnation of undigested meat with epigastric distension, diarrhea and abdominal pain; amenorrhea due to blood stasis, epigastric pain or abdominal colic after childbirth; hyperlipidemia

Precautions  :

Dosage  : 9 to 12 g.

Storage  : Preserve in a ventilated and dry place, protected from moth.

Synonymns for Crataegus pinnatifida var. major

Patent Medicines and Medicines with Multiple Ingredients that include Crataegus pinnatifida var. major

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Crataegus pinnatifida var. major in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Chao-Ran Li, Xi-Hong Hou, Yin-Yue Xu, Wen Gao, Ping Li, Hua Yang
Manual annotation combined with untargeted metabolomics for chemical characterization and discrimination of two major crataegus species based on liquid chromatography quadrupole time-of-flight mass spectrometry.
J Chromatogr A: 2020, 1612;460628
[PubMed:31753484] [WorldCat.org] [DOI] (I p)

Rugang Zhu, Mengling Hong, Chunyun Zhuang, Lijiao Zhang, Congya Wang, Jianli Liu, Zhenhua Duan, Feifei Shang, Fengqing Hu, Tiejing Li, Chong Ning, Gang Chen
Pectin oligosaccharides from hawthorn (Crataegus pinnatifida Bunge. Var. major) inhibit the formation of advanced glycation end products in infant formula milk powder.
Food Funct: 2019, 10(12);8081-8093
[PubMed:31735943] [WorldCat.org] [DOI] (I p)

Xiao Du, Xiao Zhang, Haidong Bu, Ticao Zhang, Yongchun Lao, Wenxuan Dong
##Title##
Front Plant Sci: 2019, 10;443
[PubMed:31024604] [WorldCat.org] [DOI] (P e)

Rugang Zhu, Xinyu Zhang, Yu Wang, Lijiao Zhang, Congya Wang, Fengqing Hu, Chong Ning, Gang Chen
Pectin oligosaccharides from hawthorn (Crataegus pinnatifida Bunge. Var. major): Molecular characterization and potential antiglycation activities.
Food Chem: 2019, 286;129-135
[PubMed:30827585] [WorldCat.org] [DOI] (I p)

Jianyong Zhang, Rixin Liang, Lan Wang, Bin Yang
Effects and mechanisms of Danshen-Shanzha herb-pair for atherosclerosis treatment using network pharmacology and experimental pharmacology.
J Ethnopharmacol: 2019, 229;104-114
[PubMed:30312741] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects