Cornu bubali

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Nomenclature

Other Names:

Historical Use of Cornu bubali

Cornu bubali in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Shuiniujiao

Chinese Name  :

Common Name  :Buffalo horn

Specific Name  : Cornu bubali

Scientific Name:
Collection  : The drug is boiled with water, remove from bony plug and dried.

Description  : Somewhat flattened and curved conical, varying in length. The surface brownish-black or greyish-black with several transverse grooves on one side and densely transverse depressed stripes on the other side. The upper part gradually pointed with longitudinal stripes, the basal part somewhat triangular, hollowed. Texture horny, hard, odour slightly stinky and taste weak.Identification: Powder greyish brown, Irregular broken pieces pale greyish yellow. In longitudinal section, slender spindle shaped striations with longtudinal long slits and minute greyish brown pigment granules visible, In transverse section, spindle shaped striations parallely arranged, wave with many yellowish-brown pigment granules. The surface of some broken pieces relatively even, pigment granules and slit less, poorly visible.

Identification  :

Processing  : Wash clean, cut to slices or file to coarse powder.

Action  : To remove toxic heat, to reduce heat in blood, and to arrest convulsions.

Indication  : high fever, delirium and eruptions epidemic diseases; spitting of blood, epistaxis; convulsions and mania

Precautions  :

Dosage  : 15 to 30 g, to be decocted for more than 3 hours before other ingredients.

Storage  : Preserve in a dry place, protected from mould.

P97 2.jpg

Nomenclature

Other Names:

Historical Use of Cornu bubali

Cornu bubali in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Shuiniujiao Nongsuofen

Chinese Name  :

Common Name  :Condensed buffalo horn powder

Specific Name  : Pulvis cornus bubali concentratus

Scientific Name:
Collection  : Procedure: Take Cornu Bubali, wash clean, cut with a saw, eliminate the bony plug, split into small pieces. Select the solid tip part, which is commonly known as "jiaojian" (horn tip). Immerse in 70% ethanol or sterilize with a steam the pulverized to fine powder. Break the rest, which is commonly known as "Jiaozhuang" (horn stake) to coarse granules or thin slices. Decoct 810g of the coarse granules or slices of the horn stake with 10 times of water twice for 7 - 10 hours each time. Supplement the evaporated water during decocting. Combine the decoction and filter. Concentrate the filtrate to 80 - 160ml. Add 190g of the fine powder of horn tip, mix well, dry below 80ºC, pulverize to fine powder and sift.

Description  : Pale greyish powder, odour slightly stinking, taste slightly salty.Water: Carry out the method for determination of water (Appendix lX H, method1) not more than 11.0%.

Identification  :

Processing  :

Action  : To remove toxic heat, to reduce heat in blood, and to arrest convulsions.

Indication  : high fever, delirium and eruptions epidemic diseases; spitting of blood, epistaxis; convulsions and mania

Precautions  :

Dosage  : 1.5 to 3 g, 2 times a day.

Storage  : Preserve in well closed containers, stored in a dry place, protected from moisture.

Synonymns for Cornu bubali

Patent Medicines and Medicines with Multiple Ingredients that include Cornu bubali

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Cornu bubali in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Chun-Xue Wang, Rui Liu, Da-Wei Qian, Jin-Ao Duan
[Determination of free thiols in animal horn derived traditional Chinese medicines].
Zhongguo Zhong Yao Za Zhi: 2019, 44(6);1216-1219
[PubMed:30989986] [WorldCat.org] [DOI] (P p)

Xu-zhao Liu, Li-si Zhou, Jin-xin Liu, Jing Jia, Jing-yuan Song, Lin-chun Shi
[Identification of water buffalo horn and its adulterants using COI barcode].
Yao Xue Xue Bao: 2017, 52(3);494-9
[PubMed:29979865] [WorldCat.org] (P p)

Xian-Long Cheng, Qian-Qian Zhang, Ming-Hua Li, Hua Yan, Kun-Zi Yu, Jian-Li Zhou, Shao-Ping Li, Feng Wei, Shuang-Cheng Ma
Identification of four cornua by ultra-performance liquid chromatography with time-of-flight mass spectrometry coupled with principal component analysis.
J Sep Sci: 2017, 40(8);1667-1673
[PubMed:28217946] [WorldCat.org] [DOI] (I p)

Rui Liu, Qiong Huang, Jin-Ao Duan, Zhenhua Zhu, Pei Liu, Yong Bian, Jinhua Tao, Dawei Qian
Peptidome characterization of the antipyretic fraction of Bubali Cornu aqueous extract by nano liquid chromatography with orbitrap mass spectrometry detection.
J Sep Sci: 2017, 40(2);587-595
[PubMed:27860201] [WorldCat.org] [DOI] (I p)

Rui Liu, Qiong Huang, Jinjun Shan, Jin-Ao Duan, Zhenhua Zhu, Pei Liu, Yong Bian, Er-Xin Shang, Dawei Qian
Metabolomics of the Antipyretic Effects of Bubali Cornu (Water Buffalo Horn) in Rats.
PLoS ONE: 2016, 11(7);e0158478
[PubMed:27384078] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects