Codonopsis pilosula var. modesta

Background

Fangdang ·Àµ³ Ludangshen ºµ³²Î Taishen ̨²Î Yetaishen Ұ̨²Î Chinese Name (pinyin): Dangshen

Chinese Name  :

Common Name  :Pilose Asiabell Root

Specific Name  : Radix codonopsis

Scientific Name:
Collection  : The drug is collected in autumn, wash clean and dried in the sun.

Description  : Root of Codonopsis pilosula: Long cylindrical, slightly curved, 10 - 34 cm long, 0.4 - 2 cm in diameter. Externally yellowish brown with numerous warty prominent stem scars and buds on the root stock and the apex of each stem scar sunkenly dotted, dense transverse annulations occurring below the root stock, gradually sparse up to half length of the root while the transverse rare or absent in some cultivars. Whole root showing longitudinal wrinkles and scattered transverse lenticels, frequently with blackish brown gelatinous substance at the fractured area of the rootlets. Texture slightly hard or tenacious, fracture somewhat even, cleft or striated radially, bark pale yellowish white or pale brown, wood pale yellow. Odour characteristic and aromatic, taste sweetish.Root of Codonopsis var. modesta: 10 - 35cm long, 0.5 - 2.5 cm in diameter. Externally yellowish white to pale yellow, dense transverse annulations occurring below the root stock, frequently up to over half length of the root. Fracture more cleft, bark greyish white to pale yellow, wood light yellow.Root of Codonopsis tangshen: 10 - 45 cm long, 0.5 - 2 cm in diameter. Externally greyish yellow to yellowish brown with distinctly longitudinal wrinkles. Texture slightly soft and compact, fracture less cleft, bark yellowish white, wood pale yellow.

Identification  : Transverse section: Several up to over 10 rows of cork cells, stone cells present at the outer side, single or grouped. Cortex narrow, phloem broad often with cracks at the outer side and pale yellow laticiferous tube groups scattered through out and frequently alternated with sieve tubes. Cambium in a ring, xylem vessels singly scattered or aggregated in groups, arranged radially. Parenchymatous cells containing inulin.Extractives: Carry out the hot extraction method as described under the determination of ethanol-soluble extractive (Appendix X A), using 45% ethanol as solvent not less than 55.0%

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To reinforce qi and invigorate the function of the spleen and the lungs.

Indication  : weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools; diabetes caused by internal heat

Precautions  : Incompatible with Rhizome et Radix Verstri.

Dosage  : 9 to 30 g.

Storage  : Preserve in a ventilated dry place, protected from moth.

Evidence or the Use of Codonopsis pilosula var. modesta in the Treatment of Epilepesy

1st Five Results: pubmed search

Xuewen Wang, Jiachao Kang, Xuechan Li, Pingmin Wu, Yong Huang, Yongqiang Duan, Juan Feng, Jing Wang
Codonopsis pilosula water extract delays D-galactose-induced aging of the brain in mice by activating autophagy and regulating metabolism.
J Ethnopharmacol: 2024, 327;118016
[PubMed:38462027] [WorldCat.org] [DOI] (I p)

Jie Wang, Qinqing Li, Shifeng Chu, Xin Liu, Junlong Zhang, Wenbin He
Impact of Codonopsis decoction on cerebral blood flow and cognitive function in rats with chronic cerebral ischemia.
J Ethnopharmacol: 2024, 323;117585
[PubMed:38159825] [WorldCat.org] [DOI] (I p)

Longxia Wen, Yanping Wang, Pingping Song, Zixia Wang, Zhuoshi Tang, Yina Guo, Huaqiao Yu, Fangdi Hu
##Title##
Foods: 2023, 12(24);
[PubMed:38137223] [WorldCat.org] [DOI] (P e)

Ruibin Bai, Yanping Wang, Yangyang Cao, Huaqiao Yu, Pengpeng Li, Guolin Chai, Xiaodong Li, Wen Li, Fang Cui, Fangdi Hu
Discrimination of three varieties of Codonopsis Radix based on fingerprint profiles of oligosaccharides by high performance liquid chromatography- evaporative light scattering detector combined with multivariate analysis.
J Chromatogr A: 2022, 1685;463642
[PubMed:36395248] [WorldCat.org] [DOI] (I p)

Li-Xia Li, Meng-Si Chen, Zi-Yu Zhang, Berit Smestad Paulsen, Frode Rise, Chao Huang, Bin Feng, Xing-Fu Chen, Ren-Yong Jia, Chun-Bang Ding, Shi-Ling Feng, Yang-Ping Li, Yu-Long Chen, Zhen Huang, Xing-Hong Zhao, Zhong-Qiong Yin, Yuan-Feng Zou
##Title##
Front Pharmacol: 2022, 13;937581
[PubMed:36091763] [WorldCat.org] [DOI] (P e)