Codonopsis pilosula var. modesta

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Nomenclature

Other Names:

Historical Use of Codonopsis pilosula var. modesta

Codonopsis pilosula var. modesta in Traditional Chinese Medicine

Background

Fangdang ·Àµ³ Ludangshen ºµ³²Î Taishen ̨²Î Yetaishen Ұ̨²Î Chinese Name (pinyin): Dangshen

Chinese Name  :

Common Name  :Pilose Asiabell Root

Specific Name  : Radix codonopsis

Scientific Name:
Collection  : The drug is collected in autumn, wash clean and dried in the sun.

Description  : Root of Codonopsis pilosula: Long cylindrical, slightly curved, 10 - 34 cm long, 0.4 - 2 cm in diameter. Externally yellowish brown with numerous warty prominent stem scars and buds on the root stock and the apex of each stem scar sunkenly dotted, dense transverse annulations occurring below the root stock, gradually sparse up to half length of the root while the transverse rare or absent in some cultivars. Whole root showing longitudinal wrinkles and scattered transverse lenticels, frequently with blackish brown gelatinous substance at the fractured area of the rootlets. Texture slightly hard or tenacious, fracture somewhat even, cleft or striated radially, bark pale yellowish white or pale brown, wood pale yellow. Odour characteristic and aromatic, taste sweetish.Root of Codonopsis var. modesta: 10 - 35cm long, 0.5 - 2.5 cm in diameter. Externally yellowish white to pale yellow, dense transverse annulations occurring below the root stock, frequently up to over half length of the root. Fracture more cleft, bark greyish white to pale yellow, wood light yellow.Root of Codonopsis tangshen: 10 - 45 cm long, 0.5 - 2 cm in diameter. Externally greyish yellow to yellowish brown with distinctly longitudinal wrinkles. Texture slightly soft and compact, fracture less cleft, bark yellowish white, wood pale yellow.

Identification  : Transverse section: Several up to over 10 rows of cork cells, stone cells present at the outer side, single or grouped. Cortex narrow, phloem broad often with cracks at the outer side and pale yellow laticiferous tube groups scattered through out and frequently alternated with sieve tubes. Cambium in a ring, xylem vessels singly scattered or aggregated in groups, arranged radially. Parenchymatous cells containing inulin.Extractives: Carry out the hot extraction method as described under the determination of ethanol-soluble extractive (Appendix X A), using 45% ethanol as solvent not less than 55.0%

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To reinforce qi and invigorate the function of the spleen and the lungs.

Indication  : weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools; diabetes caused by internal heat

Precautions  : Incompatible with Rhizome et Radix Verstri.

Dosage  : 9 to 30 g.

Storage  : Preserve in a ventilated dry place, protected from moth.

Synonymns for Codonopsis pilosula var. modesta

Patent Medicines and Medicines with Multiple Ingredients that include Codonopsis pilosula var. modesta

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Codonopsis pilosula var. modesta in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Yuan-Feng Zou, Yan-Yun Zhang, Yu-Ping Fu, Kari Tvete Inngjerdingen, Berit Smestad Paulsen, Bin Feng, Zhong-Kai Zhu, Li-Xia Li, Ren-Yong Jia, Chao Huang, Xu Song, Cheng Lv, Gang Ye, Xiao-Xia Liang, Chang-Liang He, Li-Zi Yin, Zhong-Qiong Yin
##Title##
Molecules: 2019, 24(20);
[PubMed:31600890] [WorldCat.org] [DOI] (I e)

Jiankuan Li, Xin Zhang, Lingya Cao, Jiaojiao Ji, Jianping Gao
Three Inulin-Type Fructans from Codonopsis pilosula (Franch.) Nannf. Roots and Their Prebiotic Activity on Bifidobacterium longum.
Molecules: 2018, 23(12);
[PubMed:30501018] [WorldCat.org] [DOI] (I e)

Ruibin Bai, Wuyan Li, Yingdong Li, Ming Ma, Yanping Wang, Jing Zhang, Fangdi Hu
Cytotoxicity of two water-soluble polysaccharides from Codonopsis pilosula Nannf. var. modesta (Nannf.) L.T.Shen against human hepatocellular carcinoma HepG2 cells and its mechanism.
Int. J. Biol. Macromol.: 2018, 120(Pt B);1544-1550
[PubMed:30248423] [WorldCat.org] [DOI] (I p)

Yu-Ping Fu, Bin Feng, Zhong-Kai Zhu, Xin Feng, Shu-Fan Chen, Li-Xia Li, Zhong-Qiong Yin, Chao Huang, Xing-Fu Chen, Bing-Zhao Zhang, Ren-Yong Jia, Xu Song, Cheng Lv, Gui-Zhou Yue, Gang Ye, Xiao-Xia Liang, Chang-Liang He, Li-Zi Yin, Yuan-Feng Zou
##Title##
Molecules: 2018, 23(7);
[PubMed:30037030] [WorldCat.org] [DOI] (I e)

Yu-Ping Fu, Li-Xia Li, Bing-Zhao Zhang, Berit Smestad Paulsen, Zhong-Qiong Yin, Chao Huang, Bin Feng, Xing-Fu Chen, Ren-Rong Jia, Xu Song, Xue-Qin Ni, Bo Jing, Fa-Ming Wu, Yuan-Feng Zou
Characterization and prebiotic activity in vitro of inulin-type fructan from Codonopsis pilosula roots.
Carbohydr Polym: 2018, 193;212-220
[PubMed:29773375] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects