Codonopsis pilosula

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Other Names:

Historical Use of Codonopsis pilosula

Codonopsis pilosula in Traditional Chinese Medicine


Fangdang ·Àµ³ Ludangshen ºµ³²Î Taishen ̨²Î Yetaishen Ұ̨²Î Chinese Name (pinyin): Dangshen

Chinese Name  :

Common Name  :Pilose Asiabell Root

Specific Name  : Radix codonopsis

Scientific Name:
Collection  : The drug is collected in autumn, wash clean and dried in the sun.

Description  : Root of Codonopsis pilosula: Long cylindrical, slightly curved, 10 - 34 cm long, 0.4 - 2 cm in diameter. Externally yellowish brown with numerous warty prominent stem scars and buds on the root stock and the apex of each stem scar sunkenly dotted, dense transverse annulations occurring below the root stock, gradually sparse up to half length of the root while the transverse rare or absent in some cultivars. Whole root showing longitudinal wrinkles and scattered transverse lenticels, frequently with blackish brown gelatinous substance at the fractured area of the rootlets. Texture slightly hard or tenacious, fracture somewhat even, cleft or striated radially, bark pale yellowish white or pale brown, wood pale yellow. Odour characteristic and aromatic, taste sweetish.Root of Codonopsis var. modesta: 10 - 35cm long, 0.5 - 2.5 cm in diameter. Externally yellowish white to pale yellow, dense transverse annulations occurring below the root stock, frequently up to over half length of the root. Fracture more cleft, bark greyish white to pale yellow, wood light yellow.Root of Codonopsis tangshen: 10 - 45 cm long, 0.5 - 2 cm in diameter. Externally greyish yellow to yellowish brown with distinctly longitudinal wrinkles. Texture slightly soft and compact, fracture less cleft, bark yellowish white, wood pale yellow.

Identification  : Transverse section: Several up to over 10 rows of cork cells, stone cells present at the outer side, single or grouped. Cortex narrow, phloem broad often with cracks at the outer side and pale yellow laticiferous tube groups scattered through out and frequently alternated with sieve tubes. Cambium in a ring, xylem vessels singly scattered or aggregated in groups, arranged radially. Parenchymatous cells containing inulin.Extractives: Carry out the hot extraction method as described under the determination of ethanol-soluble extractive (Appendix X A), using 45% ethanol as solvent not less than 55.0%

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To reinforce qi and invigorate the function of the spleen and the lungs.

Indication  : weakness of the spleen and the lung manifested by shortness of breath, cough, palpitation, anorexia, loose stools; diabetes caused by internal heat

Precautions  : Incompatible with Rhizome et Radix Verstri.

Dosage  : 9 to 30 g.

Storage  : Preserve in a ventilated dry place, protected from moth.

Synonymns for Codonopsis pilosula

Patent Medicines and Medicines with Multiple Ingredients that include Codonopsis pilosula

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Codonopsis pilosula in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Dongmei Chen, Jiajia Liu, Jie Meng, Dandan Li, Pan Zhao, Yongqiang Duan, Jing Wang
Integrative Analysis of Long Non-Coding RNAs (lncRNAs), miRNAs, and mRNA-Associated ceRNA Network in Lung Tissue of Aging Mice and Changes After Treatment with Codonopsis pilosula.
Med. Sci. Monit.: 2020, 26;e921580
[PubMed:32049955] [] [DOI] (I e)

Lijun Liang, Zhigui He, Haizheng Yu, Erhuan Wang, Xiaojiang Zhang, Bingxue Zhang, Chenlu Zhang, Zongsuo Liang
Selection and Validation of Reference Genes for Gene Expression Studies in Codonopsis pilosula Based on Transcriptome Sequence Data.
Sci Rep: 2020, 10(1);1362
[PubMed:31992780] [] [DOI] (I e)

Bianxia Bai, Jiahong Ren, Fenling Bai, Lin Hao
Selection and validation of reference genes for gene expression studies in Pseudomonas brassicacearum GS20 using real-time quantitative reverse transcription PCR.
PLoS ONE: 2020, 15(1);e0227927
[PubMed:31986172] [] [DOI] (I e)

Jin-Song Su, Fu-Ying Qin, Ying Liu, Yi Zhang
Nat. Prod. Res.: 2020;1-8
[PubMed:31960727] [] [DOI] (I a)

Mingying Cao, Cheng Yu, Zhuhua Yao, Xuemei Gao, Shuxing Wu
Atractylodesin III maintains mitochondrial function and inhibits caspase-3 activity to reverse apoptosis of cardiomyocytes in AMI rats.
Int J Clin Exp Pathol: 2019, 12(1);198-204
[PubMed:31933734] [] (I e)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects