Changium smyrnioides

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Nomenclature

Other Names:

Historical Use of Changium smyrnioides

Changium smyrnioides in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Mingdangshen

Chinese Name  :

Common Name  :Medicinal Changium Root

Specific Name  : Radix changii

Scientific Name:
Collection  : The drug is collected in April and May, removed from rootlet, washed clean, treated with boiling water until the cut surface is devoid of white core then taken out to scrape off the outer bark, and dried after rinsing.

Description  : Slenderly cylindrical, long fusiform or irregularly stripe shaped, 6 - 20cm long, 0.5 - 2cm in diameter. Externally yellowish white or brownish, smooth or with longitudinal furrows and rootlet scar, some showing many reddish-brown mottles. Texture hard and fragile, fracture horny, bark relatively thin, yellowish white, sometimes easily separated from whitish wood. Odour slight and taste weak.

Identification  : Carry out the cold maceration method under the determination of water soluble extractives (Appendix X A), not less than 20.0%

Processing  : Wash clean, soften thoroughly, cut into thick slices and dry.

Action  : To moisten the lung and resolve phlegm, mourish yin and regulate the function of stomach, to subdue hyperactivity of the liver, and to counteract toxicity.

Indication  : cough caused by heat in the lung; vomiting, regurgitaion, anorexia, dryness of the mouth; bloodshot eyes and vertigo; boils and sores

Precautions  :

Dosage  : 6 to 12 g.

Storage  : Preserve in a ventilated dry place, protected from moisture and moth.

Synonymns for Changium smyrnioides

Patent Medicines and Medicines with Multiple Ingredients that include Changium smyrnioides

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Changium smyrnioides in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Lu-Jing Lei, Wen-Le Wang, Jie Wang, Li-Juan Lv, Min-Hui Li
A review of the ethnopharmacology, phytochemistry, and pharmacology of Changium smyrnioides Wolff.
J Nat Med: 2019, 73(1);1-10
[PubMed:30182179] [WorldCat.org] [DOI] (I p)

Chang-Lin Wang, Qiao-Sheng Guo, Bo-Xing Cheng
[Analysis on character of mineral elements in Changium smyrnioides and rhizosphere soil].
Zhongguo Zhong Yao Za Zhi: 2018, 43(8);1579-1587
[PubMed:29751703] [WorldCat.org] [DOI] (P p)

Jing Cai, Yun Ma, Jian-Wei Chen, Xiang Li, Ping Zhou
[Effects of methyl jasmonate on accumulation of furanocoumarins in Changium smyrnioides and its suspension cells].
Zhongguo Zhong Yao Za Zhi: 2017, 42(1);76-82
[PubMed:28945028] [WorldCat.org] [DOI] (P p)

Chang-Lin Wang, Qiao-Sheng Guo, Zai-Biao Zhu, Bo-Xing Cheng
Physiological characteristics, dry matter, and active component accumulation patterns of Changium smyrnioides in response to a light intensity gradient.
Pharm Biol: 2017, 55(1);581-589
[PubMed:27937676] [WorldCat.org] [DOI] (I p)

Ping Zhou, Chen-qiong Xie, Jian-wei Chen, Xiang Li
[Effects of Browning Inhibitors on Suspension Cells Growth and Secondary Metabolites Production in Changium smyrnioides].
Zhong Yao Cai: 2015, 38(11);2250-4
[PubMed:27356372] [WorldCat.org] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects