Chaenomeles speciosa

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Nomenclature

Other Names:

Historical Use of Chaenomeles speciosa

Chaenomeles speciosa in Traditional Chinese Medicine

Background

Chenmugua ³Âľ¹Ï Xuanmugua Ðûľ¹Ï Chinese Name (pinyin): Mugua

Chinese Name  :

Common Name  :Chaenomeles Fruit

Specific Name  : Fructus chaenomelis

Scientific Name:
Collection  : The drug is collected in summer and autumn when the fruit turns greenish yellow, boiled in water until the exocarp becomes greyish white in color, halved longitudinally and dried in the sun.

Description  : Mostly in longitudinally oblong halves, 4 - 9cm long, 2 - 5cm wide, 1 - 2.5cm thick. Externally purplish red or reddish brown with irregular, deep wrinkles, edge of cut surface rolled inwards, pulp reddish brown, central part dented, brownish yellow. Seed long triangular, mostly falling off. Texture hard, odor slightly aromatic and taste sour.

Identification  : To 1g of the powder add 10ml of 70% ethanol, het under reflux for 1 hour and filter. Carry out the following test on the filtrate.1.Evaporate 1ml of filtrate to dryness and dissolve the residue in 1ml of acetic anhydride in the test tube. Add along the tube wall 1 - 2 drops of sulfuric acid, a purplish red color is produced at the junction of the two layers, a brownish yellow color is shown at the upper phase.2.Spot the filtrate on a piece of a filter paper, allow to dry and spray with aluminum chloride TS. Allow it to dry and examine under ultra violet light (365nm), a blu fluorescence is shown.Acidity: To 5g of the powder add 50ml of water, shake well, allow to stand for 1 hour and filter. PH of the filtrate, 3 - 4

Processing  : Wash clean, soften or steam thoroughly, cut into thin slices and dry it in the sun.

Action  : To lessen contracture, regulate stomach function, and dispel damp.

Indication  : arthritis with ankylosis, aching with feeling of heaviness in the loins and knees; systremma due to vomiting and diarrhea; edema and weakness of the legs

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place, protected from moisture and moth.

Synonymns for Chaenomeles speciosa

Patent Medicines and Medicines with Multiple Ingredients that include Chaenomeles speciosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Chaenomeles speciosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Igor Piotr Turkiewicz, Aneta Wojdyło, Karolina Tkacz, Paulina Nowicka, Tomasz Golis, Przemysław Bąbelewski
##Title##
Antioxidants (Basel): 2020, 9(1);
[PubMed:31936619] [WorldCat.org] [DOI] (P e)

Haibo He, Minlu Feng, Haiyan Xu, Xiaomei Li, Yumin He, Huilin Qin, Yongfeng Zhang, Hongbo Tang, Kun Zou
Total triterpenoids from the fruits of Chaenomeles speciosa exerted gastroprotective activities on indomethacin-induced gastric damage via modulating microRNA-423-5p-mediated TFF/NAG-1 and apoptotic pathways.
Food Funct: 2020, 11(1);662-679
[PubMed:31895380] [WorldCat.org] [DOI] (I p)

Yuanyuan Zhang, Haiyan Xu, Haibo He, Xiaomei Li, Minlu Feng, Yumin He, Weijie Jiang, Junzhi Wang, Daoxiang Xu, Kun Zou
Total triterpenes from the fruits of Chaenomeles speciosa (Sweet) Nakai protects against indomethacin-induced gastric mucosal injury: involvement of TFF1-mediated EGF/EGFR and apoptotic pathways.
J. Pharm. Pharmacol.: 2020, 72(3);409-423
[PubMed:31863472] [WorldCat.org] [DOI] (I p)

Jing Ma, Wenlong He, Chongyang Gao, Ruiyun Yu, Peng Xue, Yongchao Niu
[Glucosides of chaenomeles speciosa attenuate ischemia/reperfusion-induced brain injury by regulating NF-κB P65/TNF-α in mouse model].
Zhejiang Da Xue Xue Bao Yi Xue Ban: 2019, 48(3);289-295
[PubMed:31496161] [WorldCat.org] (P p)

Hai-Bo He, Xiao-Qin Li, Xiao-Mei Li, Yu-Min He, Hui-Lin Qin, Yong-Feng Zhang, Xing-Jun Xiong, Jun-Zhi Wang, Kun Zou
[Therapeutic effect of total triterpenoids of Chaenomeles speciosa combined with omeprazole on gastric ulcer induced by indomethacin in rats].
Zhongguo Zhong Yao Za Zhi: 2019, 44(11);2338-2347
[PubMed:31359661] [WorldCat.org] [DOI] (P p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects