Centella asiatica

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Other Names:

Historical Use of Centella asiatica

Centella asiatica in Traditional Chinese Medicine


Chinese Name (pinyin): Jixuecao

Chinese Name  :

Common Name  :Asiatic pennywort herb

Specific Name  : Herba centellae

Scientific Name:
Collection  : The drug is collected in summer and autumn, remove from soil and dried in the sun.

Description  : Frequently crumpled into masses, roots cylindrical, 2 - 4cm long, 1 - 1.5mm in diameter, externally pale yellow or greyish yellow. Stems slender and curved, yellowish brown, finely striated longitudinally, frequently with rootlets on the nodes. Leaves mostly crumpled and broken when whole, subrounded or kidney shaped, 1 - 4cm in diameter, greyish green, margin roughly crenate petioles 3 - 6cm long, twisted. Umbels axillary small. Cremocarps oblate with distinctly prominenet, longitudinal ridges and fine reticulate striations, fruit stalk very short, odor slight and taste weak.

Identification  :

Processing  : Eliminate foreign matter, wash clean cut into sections and dry in the sun.

Action  : To remove heat and damp, to counteract toxicity, and to cause subsidence of swelling.

Indication  : jaundice caused by damp-heat; heat stroke with diarrhea; urolithiasis and hematuria; carbuncles and boils; traumatic injuries

Precautions  :

Dosage  : 15 to 30 g; or 30 to 60 g of the fresh herb.

Storage  : Preserve in a dry place.

Synonymns for Centella asiatica

Patent Medicines and Medicines with Multiple Ingredients that include Centella asiatica

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Centella asiatica in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Claire L Hoban, Ian F Musgrave, Roger W Byard, Christine Nash, Rachael Farrington, Garth Maker, Elly Crighton, Michael Bunce, Megan Coghlan
Combined Liquid Chromatography-mass Spectrometry and Next-generation DNA Sequencing Detection of Adulterants and Contaminants in Analgesic and Anti-inflammatory Herbal Medicines.
Pharmaceut Med: 2019;
[PubMed:32048209] [WorldCat.org] [DOI] (I a)

Hanita Mohd Hussin, Mahazura Mat Lawi, Nor Hazla Mohamed Haflah, Abdul Yazid Mohd Kassim, Ruszymah Bt Hj Idrus, Yogeswaran Lokanathan
Centella asiatica (L.)-Neurodifferentiated Mesenchymal Stem Cells Promote the Regeneration of Peripheral Nerve.
Tissue Eng Regen Med: 2020;
[PubMed:32036567] [WorldCat.org] [DOI] (I a)

Yonghyeon Lee, Hyeon Kyeong Choi, Kaudjhis Patrick Ulrich N'deh, Young-Jin Choi, Meiqi Fan, Eun-Kyung Kim, Kang-Hyun Chung, And Jeung Hee An
Inhibitory Effect of Centella asiatica Extract on DNCB-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice.
Nutrients: 2020, 12(2);
[PubMed:32033291] [WorldCat.org] [DOI] (I e)

Juan M Pericàs, Jaume Llopis, Patricia Muñoz, Juan Gálvez-Acebal, Martha Kestler, Maricela Valerio, Marta Hernández-Meneses, Miguel Á Goenaga, Manuel Cobo-Belaustegui, Miguel Montejo, Guillermo Ojeda-Burgos, M Dolores Sousa-Regueiro, Arístides de Alarcón, Antonio Ramos-Martínez, José M Miró, GAMES Investigators
A Contemporary Picture of Enterococcal Endocarditis.
J. Am. Coll. Cardiol.: 2020, 75(5);482-494
[PubMed:32029130] [WorldCat.org] [DOI] (I p)

Giulia Sbrini, Paola Brivio, Marco Fumagalli, Flavio Giavarini, Donatella Caruso, Giorgio Racagni, Mario Dell'Agli, Enrico Sangiovanni, Francesca Calabrese
Nutrients: 2020, 12(2);
[PubMed:32013132] [WorldCat.org] [DOI] (I e)



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Pregnancy and Breastfeeding

Adverse Effects