Brucea javanica

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Nomenclature

Other Names:

Historical Use of Brucea javanica

Brucea javanica in Traditional Chinese Medicine

Background

Yadanyou Ñ»µ¨ÓÍ Chinese Name (pinyin): Yadanzi

Chinese Name  :

Common Name  :Brucea Fruit

Specific Name  : Fructus bruceae

Scientific Name:
Collection  : The drug is collected in autumn when ripe, removed from foreign matter and dried in the sun.

Description  : Ovoid, 6 - 10mm long, 4 - 7mm in diameter. Externally black or brown with raised reticulate wrinkles, lumina irregularly polygonal, obviously ribbed at both sides. Apex acuminate, base having a dented fruit stalk scar, shell hard and brittle. Seeds ovoid, 5 - 6mm long, 3 - 5mm in diameter, externally whitish or yellowish white with reticulate, testa thin, cotyledons milky white oily. Odorless, taste extremely bitter.

Identification  : Powder opf pericarp: Epidermal cells polygonal, containing brown contents, parenchymatous cells polygonal, containing clusters of calcium oxalate up to 30µm in diameter and prisms. Stone cells subrounded or polygonal, 14 - 38µm in diameter.Powder of seed: yellowish white. The cells of testa polygonal, slightly elongated. The cells of endosperm and cotyledon containing aleurone grains.

Processing  : Eliminate shells and foreign matter.

Action  : To remove toxic heat, to stop malarial attacks, to relieve dysentery, and to cauterize vegetations.

Indication  : dysentery, malaria external: vegetation, corn

Precautions  :

Dosage  : 0.5 to 2 g to be taken after wrapped in Arillus Longan or in capsules; appropraite quantity for external use.

Storage  : Preserve in a dry place.

Synonymns for Brucea javanica

Patent Medicines and Medicines with Multiple Ingredients that include Brucea javanica

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Brucea javanica in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Pandu Ishaq Nandana, Haerani Rasyid, Prihantono Prihantono, Ika Yustisia, Lukman Hakim, Agussalim Bukhari, Eka Sunarwidhi Prasedya
Cytotoxicity and Apoptosis Studies of Brucein D against T24 Bladder Cancer Cells.
Asian Pac J Cancer Prev: 2024, 25(3);921-930
[PubMed:38546074] [WorldCat.org] [DOI] (I e)

Zelei Dai, Chenfeng Tan, Jun Wang, Qin Wang, Ying Wang, Ying He, Yalan Peng, Mingyou Gao, Yonggang Zhang, Lei Liu, Ningying Song, Nian Li
Traditional Chinese medicine for gastric cancer: An evidence mapping.
Phytother Res: 2024;
[PubMed:38517014] [WorldCat.org] [DOI] (I a)

Huiyun Zhang, Yu Zhang, Yunfei Hu, Shunru Wei, Michael Adu-Frimpong, Congyong Sun, Gang Qi
##Title##
Drug Dev Ind Pharm: 2024;1-9
[PubMed:38466185] [WorldCat.org] [DOI] (I a)

Jinglei Miao, Shijie Chen, Hongqing Cao, Zhiyu Ding, Yuezhan Li, Weiguo Wang, Keshav Nundlall, Youwen Deng, Jinsong Li
Bruceantinol targeting STAT3 exerts promising antitumor effects in in vitro and in vivo osteosarcoma models.
Mol Carcinog: 2024;
[PubMed:38426797] [WorldCat.org] [DOI] (I a)

Wenyi Xi, Chenhui Zhao, Zeyu Wu, Tongtong Ye, Rui Zhao, Xiaochun Jiang, Shizhang Ling
Brusatol's anticancer activity and its molecular mechanism: a research update.
J Pharm Pharmacol: 2024;
[PubMed:38394388] [WorldCat.org] [DOI] (I a)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects