Bolbostemma paniculatum

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Other Names:

Historical Use of Bolbostemma paniculatum

Bolbostemma paniculatum in Traditional Chinese Medicine


Chinese Name (pinyin): Tubeimu

Chinese Name  :

Common Name  :Paniculate Bolbostemma

Specific Name  : Rhizoma bolbostemmae

Scientific Name:
Collection  : The drug is collected in autumn, wash clean, broken off, boiled until no white core observe and dried in the sun.

Description  : Irregular masses varying in size, externally reddish brown or dark brown, bumpy. Texture hard, uneasily broken, fracture horny, bright and smooth, odour slight, taste slightly bitter.

Identification  :

Processing  :

Action  : To dissolve lumps, cause subsidence of swelling, and counteract toxicity.

Indication  : mastitis, chronic lymphadenitis, tuberculosis of cervical lymph nodes, hypertrophic rhinitis

Precautions  :

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Bolbostemma paniculatum

Patent Medicines and Medicines with Multiple Ingredients that include Bolbostemma paniculatum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Bolbostemma paniculatum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Mingli Yang, Jian Xie, Xiaocan Lei, Zhifu Song, Yadong Gong, Haiyan Liu, Lin Zhou
Tubeimoside I suppresses diabetes-induced bone loss in rats, osteoclast formation, and RANKL-induced nuclear factor-κB pathway.
Int. Immunopharmacol.: 2020, 80;106202
[PubMed:32004923] [] [DOI] (I p)

Jian-Wei Dou, Rong-Guo Shang, Xiao-Qin Lei, Kang-Le Li, Zhan-Zi Guo, Kai Ye, Xiao-Juan Yang, Yu-Wei Li, Yun-Yun Zhou, Jia Yao, Qian Huang
Total saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway.
BMC Complement Altern Med: 2019, 19(1);304
[PubMed:31703679] [] [DOI] (I e)

Xu Chao, Guoquan Wang, Yuping Tang, Changhu Dong, Hong Li, Bin Wang, Jieqiong Wu, Jiarong Zhao
The effects and mechanism of peiminine-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
PLoS ONE: 2019, 14(1);e0201864
[PubMed:30615617] [] [DOI] (I e)

Md Sodrul Islam, Chenying Wang, Jingyou Zheng, Narayan Paudyal, Yongliang Zhu, Hongxiang Sun
The potential role of tubeimosides in cancer prevention and treatment.
Eur J Med Chem: 2019, 162;109-121
[PubMed:30439592] [] [DOI] (I p)

Xianling Gong, Ruibo Sun, Zhuowei Gao, Weili Han, Yawei Liu, Liang Zhao, Linlin Jing, Xueqing Yao, Xuegang Sun
Tubeimoside 1 Acts as a Chemotherapeutic Synergist via Stimulating Macropinocytosis.
Front Pharmacol: 2018, 9;1044
[PubMed:30319403] [] [DOI] (P e)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects