Black Hellebore

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Black Hellebore is a non-scientific common name that may refer to a number of plant species and varieties.

Nomenclature

Other Names:

Historical Use of Black Hellebore

Black Hellebore in Traditional Chinese Medicine

Description

Historical Use of Black Hellebore in Western Medicine

Quote Paraph: "One or two days preceeding the attack (provided that the attacks follow a definite rhythm),…. Purged with medicaments; sometimes with … cathartics (e.g., or black hellebore),"
Sec Auth: Temkin O
Title: The Falling Sickness. Second Edition, Revised, Softshell Books edition, 1994
Page: 68
Source: The Falling Sickness, Second Edition, Revised, Softshell Books edition, 1994,Owsei Temkin
Complete: Temkin O. The falling sickness: a history of epilepsy from the Greeks to the beginnings of modern neurology. London: Johns Hopkins Univ. Press, 2 Revised Edition, (Softshell Books) ; 1994. p. 68.
Primary Source: 435 Cf. Caelius Aurelianus, l.c., par. 136., p 22.

Background

Synonymns for Black Hellebore

Patent Medicines and Medicines with Multiple Ingredients that include Black Hellebore

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Black Hellebore in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Pei Li, Jie Shen, Zhiqiang Wang, Shuangshuang Liu, Qing Liu, Yue Li, Chunnian He, Peigen Xiao
Genus Paeonia: A comprehensive review on traditional uses, phytochemistry, pharmacological activities, clinical application, and toxicology.
J Ethnopharmacol: 2021, 269;113708
[PubMed:33346027] [WorldCat.org] [DOI] (I p)

Théo Brillatz, Maxime Jacmin, Konstantina Vougogiannopoulou, Eleftherios A Petrakis, Eleftherios Kalpoutzakis, Joëlle Houriet, Léonie Pellissier, Adriano Rutz, Laurence Marcourt, Emerson Ferreira Queiroz, Alexander D Crawford, Alexios-Leandros Skaltsounis, Jean-Luc Wolfender
Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles.
J Ethnopharmacol: 2020, 259;112954
[PubMed:32445663] [WorldCat.org] [DOI] (I p)

K Laios, P Lytsikas-Sarlis, K Manes, M-I Kontaxaki, M Karamanou, G Androutsos
Drugs for mental illnesses in ancient greek medicine.
Psychiatriki: 2019, 30(1);58-65
[PubMed:31115355] [WorldCat.org] [DOI] (I p)

Yue Cong, Yu-Bo Zhou, Jing Chen, Yi-Mei Zeng, Jin-Hui Wang
Alkaloid profiling of crude and processed Veratrum nigrum L. through simultaneous determination of ten steroidal alkaloids by HPLC-ELSD.
J Pharm Biomed Anal: 2008, 48(3);573-8
[PubMed:18599245] [WorldCat.org] [DOI] (P p)

Yoojin Choi, Paul R Borghesani, Jennifer A Chan, Rosalind A Segal
Migration from a mitogenic niche promotes cell-cycle exit.
J Neurosci: 2005, 25(45);10437-45
[PubMed:16280582] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects