Aucklandia lappa

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Nomenclature

Other Names:

Historical Use of Aucklandia lappa

Aucklandia lappa in Traditional Chinese Medicine

Background

Guangmuxiang ¹ãľÏã Weimuxiang ìÐľÏã Yunmuxiang ÔÆľÏã Chinese Name (pinyin): Muxiang

Chinese Name  :

Common Name  :Aucklandia Root

Specific Name  : Radix aucklandiae

Scientific Name:
Collection  : The drug is collected in winter and spring, removed from soil and rootlets, cut into section and the large further longitudinally cut into pieces, dried and removed from the rough outer bark dashing.

Description  : Cylindrical or semicylindrical, 5 - 10 cm long, 0.5 - 5 cm in diameter. Externally yellowish brown to greyish brown with distinct wrinkles, longitudinal furrows and lateral root scars. Texture hard, uneasily broken, fracture greyish brown to dark brown, the outer layer greyish yellow or brownish yellow, cambium ring brown, having radial lines and scattered brown dotted oil cavities. Odour characteristic and aromatic, taste slightly bitter.

Identification  : 1.Powder: Yellowish green, inulin more frequent with radial striations. Xylem fibres mostly in bundles, long fusiform, 16 - 24 µm in diameter, pit apertures horizontal-porous, crisscross or V-shaped. Reticulate vessels more frequent, bordered pitted vessels present. 30 - 90µm in diameter. Fragments of oil cavities visible containing yellow or brown contents.2.Soften the section of the drug with 70% ethanol then add 1 drop of each of 5% a-naphthol solution and sulfuric acid, a violet colour is produced.Total ash: Not more than 4.0%

Processing  : Eliminate foreign matter, wash clean, soak briefly, soften thoroughly, cut into thick slices and dry in the shade. Occurring in subrounded thick slices, 15 - 30 cm in diameter, externally greyish brown or brown, the center marked with crysanthemum flower like radial lines and dark brown annulations at intervals, oil dots (oil cavities) brown and scattered throughout. The peripheral outer layer yellowish brown or greyish brown wrinkled longitudinally. Texture hard, odour, characteristic, aromatic, taste bitter.Radix Aucklandiae (roasted (roasted): Spread undried Radix Aucklandia on paper made of straw and piled up consecutively in style of covering one layer of the drug. With one layer of paper in wired shallow basket, roast on a coke stove or in a drying shed until volatile oil is absorbed by paper and take it out.

Action  : To relieve pain by promoting the flow of qi, and to remove digestion by reinforcing the spleen function. Radix Aucklandiae (roasted): Diarrhea with abdominal pain.

Indication  : distending pain in the chest and epigastrium; tenesms in dysentery; indigestion with anorexia

Precautions  :

Dosage  : 1.5 to 6 g.

Storage  : Preserve in a dry place, protected from moisture.

Synonymns for Aucklandia lappa

Patent Medicines and Medicines with Multiple Ingredients that include Aucklandia lappa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Aucklandia lappa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Qing Zhou, Wei-Xin Zhang, Zong-Qi He, Ben-Sheng Wu, Zhao-Feng Shen, Hong-Tao Shang, Tuo Chen, Qiong Wang, Yu-Gen Chen, Shu-Tang Han
The Possible Anti-Inflammatory Effect of Dehydrocostus Lactone on DSS-Induced Colitis in Mice.
Evid Based Complement Alternat Med: 2020, 2020;5659738
[PubMed:32082397] [WorldCat.org] [DOI] (P e)

Ren Zhang, Ji Hao, Kaiwen Guo, Wanxin Liu, Fei Yao, Qingming Wu, Chang Liu, Qiang Wang, Xinzhou Yang
Germacrone Inhibits Cell Proliferation and Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cells.
Biomed Res Int: 2020, 2020;7643248
[PubMed:32071920] [WorldCat.org] [DOI] (I e)

Yuanyuan Chen, Ruisheng Li, Zhilei Wang, Xiaorong Hou, Chunyu Wang, Yongqiang Ai, Wei Shi, Xiaoyan Zhan, Jia-Bo Wang, Xiaohe Xiao, Zhaofang Bai, Hongsheng Sun, Guang Xu
Dehydrocostus lactone inhibits NLRP3 inflammasome activation by blocking ASC oligomerization and prevents LPS-mediated inflammation in vivo.
Cell. Immunol.: 2020, 349;104046
[PubMed:32057354] [WorldCat.org] [DOI] (I p)

Vasundhara Thakur, Savita Bains, Shivalika Pathania, Shailesh Sharma, Ravneet Kaur, Kashmir Singh
Comparative transcriptomics reveals candidate transcription factors involved in costunolide biosynthesis in medicinal plant-Saussurea lappa.
Int. J. Biol. Macromol.: 2020, 150;52-67
[PubMed:32035965] [WorldCat.org] [DOI] (I a)

Azra Batool, Ghulam Abbas Miana, Muhammad Muddassir, Mohsin Abbas Khan, Saba Zafar
In vitro cytotoxic, antioxidant, antibacterial and antifungal activity of Saussurea heteromalla indigenous to Pakistan.
Pak J Pharm Sci: 2019, 32(6(Supplementary));2771-2777
[PubMed:32024613] [WorldCat.org] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects