Aster tataricus

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Nomenclature

Other Names:

Historical Use of Aster tataricus

Aster tataricus in Traditional Chinese Medicine

Background

Zhiziwan ÖË×ÏÝÒ Chinese Name (pinyin): Ziwan

Chinese Name  :

Common Name  :Root and Rhizome of Tatarian Aster

Specific Name  : Radix asteris

Scientific Name:
Collection  : The drug is collected in spring and autumn, removed from the knotty rhizomes and soil, braided and dried in the sun or dried in the sun directly.

Description  : Rhizome in irregular masses, varying in size, apex with remains of stem and leaves. Texture slightly hard. Rhizomes bearing numerous, fascicular rrotets, 3 - 15 cm long. 0.1 - 0.3 cm in diameter, frequently braided. Externally purplish red or greyish red with longitudinal wrinkles. Texture flexible. Odour, slightly aromatic, sweet and slightly bitter.

Identification  : 1.Transverse section of root: Epidermal cells frequently withered or sometyimes sloughing, containing purplish red pigment. Hypodermal cells in a row, somewhat elongated tangentially, some containing purplish red pigment, lateral and inner walls slightly thickened. Cortex broad with intercellular spaces, secretory ducts 4 - 6 in cortex inside, endodermis distinct. Etele small, xylem somewhat polygonal, each of the phloem bundles alternating with the arc of xylem respectively, the center usually showing a pith.Rhizomes: Epidermis with glandular hairs, cortex scattered stone cells and sclerenchymatous cells. Parenchymatous cells of root and rhizomes containing inulin, sometimes containing clusters of calcium oxalate.2.Heat 2 g of the powder in 20 ml of water at 60ºC on a water bath for 10 minutes, filter while hot and allow to cool. Transfer 2 ml of filtrate to a stoppered tube, shake vigorously for 1 minute, a persistent froth is produced lasting for 10 minutes.3.To 2g of the powder add 20 ml of petroleum ether (60 - 90ºC), heat under reflux for 30 minutes and filter. Evaporate the filtrate to about 2 ml, used it as the test solution. Prepare a solution of 2g of Radix Asteris reference drug in the same manner as the reference drug solution. Carry out the method for thin layer chromatography (Appendix Vl B0, using silica gel G as the coating substance and benzene as the mobile phase. Epply 2 µl of each of the solutions to the plate. After developing and removal of the plate, dry it in the air, spray with 2.4-dinitrophenylhydrazine TS. The yellow spots in the chromatogram obtained with the test solution correspond in position and colour to the spot in the chromatogram obtained with the reference solution. Heat the plate at 105ºC for 10 minutes, the spots in the chromatogram obtained with the test solution correspond in position and colour to the spot in the chromatogram obtained with the reference solution.Total ash: Not more than 15.0% (Appendix lX K).Acid-insoluble ash: Not more than 8.0%

Processing  : Eliminate foreign matter, wash clean, soften briefly, cut into thick slices and dry.Stir fried with honey: Stir fry the slices as described under the method of stir frying with honey (Appendix ll D) until no more sticky to fingers.

Action  : To eliminate phlegm and relieve cough.

Indication  : acute or chronic cough and asthma with copious expectoration; hemoptysis in consumptive diseases

Precautions  :

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a cool and dry place, protected from moisture.

Synonymns for Aster tataricus

Patent Medicines and Medicines with Multiple Ingredients that include Aster tataricus

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Aster tataricus in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Cheng-Chuang Lin, Yuan-Yuan Wang, Si-Min Chen, Yun-Tao Liu, Ji-Qiang Li, Fang Li, Jie-Chen Dai, Tong Zhang, Feifei Qiu, Huazhen Liu, Zhenhua Dai, Zhong-De Zhang
Shegan-Mahuang Decoction ameliorates asthmatic airway hyperresponsiveness by downregulating Th2/Th17 cells but upregulating CD4+FoxP3+ Tregs.
J Ethnopharmacol: 2020, 253;112656
[PubMed:32035217] [WorldCat.org] [DOI] (I a)

Wenjuan Ma, Guangzhe Yao, Xuhua Huang, Qi Jia, Jiayuan Shen, Yanxu Chang, Huizi Ouyang, Jun He
Comparison of the active components of Aster tataricus from different regions and related processed products by ultra-high performance liquid chromatography with tandem mass spectrometry.
J Sep Sci: 2020;
[PubMed:31909569] [WorldCat.org] [DOI] (I a)

Thomas Schafhauser, Linda Jahn, Norbert Kirchner, Andreas Kulik, Liane Flor, Alexander Lang, Thibault Caradec, David P Fewer, Kaarina Sivonen, Willem J H van Berkel, Philippe Jacques, Tilmann Weber, Harald Gross, Karl-Heinz van Pée, Wolfgang Wohlleben, Jutta Ludwig-Müller
##Title##
Proc. Natl. Acad. Sci. U.S.A.: 2019;
[PubMed:31811021] [WorldCat.org] [DOI] (I a)

Xiang Dong Su, Hyun-Jae Jang, Hong Xu Li, Young Ho Kim, Seo Young Yang
Identification of potential inflammatory inhibitors from Aster tataricus.
Bioorg. Chem.: 2019, 92;103208
[PubMed:31473471] [WorldCat.org] [DOI] (I p)

Antoine Vassaux, Cédric Tarayre, Anthony Arguëlles-Arias, Philippe Compère, Frank Delvigne, Patrick Fickers, Linda Jahn, Alexander Lang, Valérie Leclère, Jutta Ludwig-Müller, Marc Ongena, Thomas Schafhauser, Samuel Telek, Ariane Théatre, Willem J H van Berkel, Micheline Vandenbol, Karl-Heinz van Pée, Luc Willems, Wolfgang Wohlleben, Philippe Jacques
Astin C Production by the Endophytic Fungus Cyanodermella asteris in Planktonic and Immobilized Culture Conditions.
Biotechnol J: 2019, 14(8);e1800624
[PubMed:31161690] [WorldCat.org] [DOI] (I p)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects