Asarum heterotropoides var. mandshuricum

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Nomenclature

Other Names:

Historical Use of Asarum heterotropoides var. mandshuricum

Asarum heterotropoides var. mandshuricum in Traditional Chinese Medicine

Background

Beixixin ±±Ï¸ÐÁ Liaoxixin ÁÉϸÐÁ Chinese Name (pinyin): Xixin

Chinese Name  :

Common Name  :Asarum Herb

Specific Name  : Herba asari

Scientific Name:
Collection  : The drug is collected at the fruiting stage in summer or in early autumn, remove from adhering soil and dried in the shade.

Description  : Herb of Asarum heterotropoides var. mandshuricum: usually rolled into a loose mass. Rhizomes of horizontal growth irregularly cylindrical, short branced, 1 --10cm long, 2 - 4mm in diameter, externally greyish brown, rough with ringed nodes, internodes 2 - 3mm long, marked with dish like stem scar at the top of a branch. Roots slender, closely born at nodes, 10 - 20cm long, 1mm in diameter, externally greyish-yellow, smooth or longitudinally wrinkled with fibrous roots or scars. Basal leaves 1 - 3 long petioled, surface glabrous, lamina mostly broken, the whole ones cordate to reniform-corrdate, margins entire, acute at the apex and deeply cordate at the base, 4 - 10cm long, 6 - 12cm wide, surface pale green. Some with flowers mostly crumpled, campanulate, dark purple, perianth-lobes incurved at the base and almost appressed to the perianth tube. Fruit hemigloboid, odour pungent-aromatic, taste pungent with tongue -numbing feeling. The rhizomes of the cultivated forms much-branched, 5 - 15cm long, 2 - 6mm in diameter. Roots 15 - 40cm long, 1 - 2mm in diameter, more leaves present.

Identification  : Foreign matter: Not more than 1% (Appendix lX A)Tootal ash: Not more than 12.0% (Appendix lX K)Assay: Carry out the method for the determination of volatile oil (Appendix X D). It contains not less than 2.0% (ml/g) of volatile oil.

Processing  : Eliminate foreign matter, spray a quantity of water, soften briefly, cut into sections and dry in the shade.

Action  : To dispel wind-cold, to relieve nasal obstruction, to alleviate pain and to remove retained fluid.

Indication  : common cold, headache, toothache; sinusitis with nasal obstruction; rheumatic arthralgia; cough and dyspnea due to retention of phlegm and fluid

Precautions  : Incompatible with Rhizome et Radix Verstri.

Dosage  : 1 to 3 g; appropriate quantity for external use.

Storage  : Preserve in a cool and dry place.

Synonymns for Asarum heterotropoides var. mandshuricum

Patent Medicines and Medicines with Multiple Ingredients that include Asarum heterotropoides var. mandshuricum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Asarum heterotropoides var. mandshuricum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Seung Eui Min, Eun-Young Gu, Jina Jung, Seng-Min Back, Woojin Kim, Byung Sun Min, Yong-Bum Kim, Kang-Hyun Han
Evaluating the toxicity of the roots of Asarum heterotropoides var. mandshuricum extracted using the decoction method: Genotoxicity, single-dose toxicity, and 13-week repeated-dose toxicity studies.
J Ethnopharmacol: 2024, 325;117783
[PubMed:38246480] [WorldCat.org] [DOI] (I p)

Hanze Liu, Suli Li, Xiaohan Huan, Yujuan Xie, Zhejun Xie, Yuting Sun, Ning Cao, Qi Xie, Yaru Wang, Hanxue Wang, Xuemei Cheng, Huida Guan, Changhong Wang
The antinociceptive and anti-inflammatory potential and pharmacokinetic study of significant alkamides ingredients from Asarum Linn.
J Ethnopharmacol: 2022, 297;115569
[PubMed:35868550] [WorldCat.org] [DOI] (I p)

Thi Thanh Le, Manh Tuan Ha, Kang-Hyun Han, Yong-Bum Kim, Jeong Ah Kim, Byung Sun Min
Anti-Inflammatory Lignans from the Roots of Asarum heterotropoides var. mandshuricum and Their Mechanism of Action.
Chem Biodivers: 2022, 19(6);e202100986
[PubMed:35502747] [WorldCat.org] [DOI] (I p)

Yingxin Sun, Qiang Ai, Zeliang Lü, Cuijing Liu
##Title##
Mitochondrial DNA B Resour: 2021, 6(9);2536-2537
[PubMed:34377821] [WorldCat.org] [DOI] (I e)

Zhiqing Wang, Haiqin Ma, Min Zhang, Ziqing Wang, Yixin Tian, Wei Li, Yingping Wang
Transcriptional response of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. leaves grown under full and partial daylight conditions.
BMC Genomics: 2021, 22(1);16
[PubMed:33407099] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects