Aristolochia contorta

Background

Zhidouling Ö˶µÁå Chinese Name (pinyin): Madouling

Chinese Name  :

Common Name  :Aristolochia Fruit

Specific Name  : Fructus aristolochiae

Scientific Name:
Collection  : The drug is collected in autumn when the fruit turns from green to yellow and dried.

Description  : Ovoid, 3 - 7cm long, 2 - 4cm in diameter. Outer surface yellowish green, greyish green or brown with 12 longitudinal ribs from the extending numerous horizontal parallel veinlets. Apex flattened and obtuse, base with slender fruit stalk. Pericarp light and fragile, easily divided into 6 splitlings. Inner surface of pericarp smooth and lustrous with dense transverse veins. Fruit 6 locular, containing many seeds in each locule, ovelapped and arranged regularly. Seeds flattened and thin, obtuse triangular or fan shaped, 6 - 10mm long, 8 - 12mm wide, winged all around, pale brown, odour charactestic, taste slightly bitter.

Identification  : to 3g of the powder add 50ml of ethanol, heat under reflux on a water bath for 1 hour, filter. Evaporate the filtrate to dryness, dissolve the residue in 5ml of ethanol as the test solution. Extract the reference drug of Fructus Aristolochiae in the same manner, use the extract as the reference solution (1), use 0.5mg per ml solution of aristolochic acid CRS in ethanol as the reference solution (2). Carry out the method for thin chromatography (Appendix Vl B) using silica gel G as the coating substance and the upper layer of toluene-ethyl acetate water-formic acid (20:10:1:1) as the mobile phase. Apply in strip separately to the plate 5µl of each of the three solutions. After developing and removal of the plate, dry it in the air and examine under ultra violet light (365nm). The fluorescent strips in the chromatogram obtained with the test solution correspond in position and color to the strips in the chromatogram obtained with the reference solutions.

Processing  : Eliminate foreign matter, sift and rub the fruit to pieces.Processed with honey: Stri fry as describe under the method of stir frying with honey (Appendix ll D) until not sticky to fingers.

Action  : To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine (rectum) for the treatment of hemorrhoid.

Indication  : asthma, cough, bloddy sputum due to heat in the lung; bleeding, swollen and painful hemorrhoids due to heat in the large intestine

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a dry place.

Background

Chinese Name (pinyin): Tianxianteng

Chinese Name  :

Common Name  :Dutchmanspipe Vine

Specific Name  : Herba aristolochiae

Scientific Name:
Collection  : The drug is collected in autumn, remove from foreign matter and dried in the sun

Description  : Stem slenderly cylindrical, slightly twisted, 1 - 3mm in diameter, externally yellowish green or pale yellowsih brown with longitudinal ridges and nodes, internodes varying in length, texture fragile, easily broken. Fracture exhibiting several vascular bundles of variable size. Leaves alternate, mostly crumpled, broken when whole, deltoid-narrow-ovate and cordate at the base. Dark green or pale yellowish brown, basal ones obviously veined, slenderly petioled, odor delicately aromatic and taste weak.

Identification  : Stem slenderly cylindrical, slightly twisted, 1 - 3mm in diameter, externally yellowish green or pale yellowsih brown with longitudinal ridges and nodes, internodes varying in length, texture fragile, easily broken. Fracture exhibiting several vascular bundles of variable size. Leaves alternate, mostly crumpled, broken when whole, deltoid-narrow-ovate and cordate at the base. Dark green or pale yellowish brown, basal ones obviously veined, slenderly petioled, odor delicately aromatic and taste weak.

Processing  : Elminate foreign matter and cut into sections.

Action  : To promote the flow of qi and blood, and to induce diuresis.

Indication  :

Precautions  :

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a dry place, protected from mould.

Evidence or the Use of Aristolochia contorta in the Treatment of Epilepesy

1st Five Results: pubmed search

Si-Hyun Park, Jae Geun Kim
##Title##
Front Plant Sci: 2024, 15;1359783
[PubMed:38571710] [WorldCat.org] [DOI] (P e)

Fanqi Meng, Sixuan Zhang, Jiaxian Su, Butuo Zhu, Xian Pan, Xiaoxiao Qiu, Xinyun Cui, Chunling Wang, Lili Niu, Caili Li, Shanfa Lu
Characterization of two CYP80 enzymes provides insights into aporphine alkaloid skeleton formation in Aristolochia contorta.
Plant J: 2024;
[PubMed:38379355] [WorldCat.org] [DOI] (I a)

Si-Hyun Park, Jae Geun Kim
##Title##
Front Plant Sci: 2023, 14;1226331
[PubMed:37810400] [WorldCat.org] [DOI] (P e)

Se Jong Jeong, Bo Eun Nam, Hyeon Jin Jeong, Jae Yeon Jang, Youngsung Joo, Jae Geun Kim
##Title##
Front Plant Sci: 2023, 14;1145363
[PubMed:37324666] [WorldCat.org] [DOI] (P e)

Si-Hyun Park, Jae Hyun Kim, Jae Geun Kim
Effects of human activities on Sericinus montela and its host plant Aristolochia contorta.
Sci Rep: 2023, 13(1);8289
[PubMed:37217596] [WorldCat.org] [DOI] (I e)