Arisaema heterophyllum

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Other Names:

Historical Use of Arisaema heterophyllum

Arisaema heterophyllum in Traditional Chinese Medicine


Shengnanxing ÉúÄÏÐÇ Zhinanxing ÖÆÄÏÐÇ Chinese Name (pinyin): Tiannanxing

Chinese Name  :

Common Name  :Arisaema Tuber

Specific Name  : Rhizoma arisaematis

Scientific Name:
Collection  : The drug is collected in autumn and winter when the stem and leaf are withered, removed from fibrous root and outer tissue and dried.

Description  : Oblate, 1 - 2 cm high, 1.5 - 6.5 cm in diameter, Externally whitish or brownish, relatively smooth. Top with dented stem scars, encircled with numerous pitted fibrous root scar, some tuber surrounded by small oblate lateral buds. Texture hard uneasily broken, fracture uneven, white and starchy, odour acrid, taste numb and pungent.

Identification  : Powder: Whitish, starch granules mainly simple, spherical oblong, 2 - 17 µm in diameter, hilum pointed, slit shaped, faint striation of large granules visible. Compound granules few, consisting of 2 - 12 components. Needle crystals of calcium oxalate scattered or in bundles embedded in mucilage cells. 63 - 131 µm long. Prisms of calcium oxalate mostly found in parenchymatous cells accompanied by vessels, 3 - 20 µm in diameter.

Processing  : Rhizoma Arisaematis (unprepared) Eliminate foreign matter, wash clean and dry.(Prepared): Take clean Rhizoma Arisaematis, grade according to size, soak in water separately and change water 2 - 3 times a day, add alumen after changing water if white foam is produced (to each 100 kg of Rhizoma Arisaematis add 2 kg of Alumen). After soaking for a day, change water again and take out when the cut surface of the drug has a taste of slight tongue-numbing sensation. Boil the slices of Rhizoma Zingeberis and Alumen in a pot with a quatity of water then add Rhizoma Arisaematis and boil until the cut surface of the drug is absent from the dry center part. Take out and removed Rhizoma Zingiberis, dry the drug in air briefly, cut into thin slices and dry thoroughly. To each 100 kg of Rhizoma Arisaematis add 12.5 kg of Rhizoma Zingiberis and 12.5 kg of Alumen.

Action  :

Indication  : intractable phlegm with cough; vertigo; stroke with phlegm in the throat, deviation of the eye and the mouth, hemiplegia; epilepsy and convulsions; tetanus. External use for boils, sores, snake and insect bites

Precautions  :

Dosage  : 3-10g

Storage  :

Synonymns for Arisaema heterophyllum

Patent Medicines and Medicines with Multiple Ingredients that include Arisaema heterophyllum

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Arisaema heterophyllum in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Sheng-Xiang Zhang, Yuan-Yuan Shi, Chen-Kai Wang, De-Rui Zhao, Qing-Shan Yang, Ke-Long Ma, Jia-Wen Wu
[Cloning and characterization of chalcone synthase and chalcone isomerase genes in Arisaema heterophyllum].
Zhongguo Zhong Yao Za Zhi: 2019, 44(9);1799-1807
[PubMed:31342705] [] [DOI] (P p)

Chenkai Wang, Jinhang Zhu, Miaomiao Liu, Qingshan Yang, Jiawen Wu, Zegeng Li
De novo sequencing and transcriptome assembly of Arisaema heterophyllum Blume and identification of genes involved in isoflavonoid biosynthesis.
Sci Rep: 2018, 8(1);17643
[PubMed:30518768] [] [DOI] (I e)

Chaoqun Tan, Dashuai Xie, Yujie Liu, Wei Peng, Xinyi Li, Li Ai, Chunjie Wu, Chuanbiao Wen, Xiwei Huang, Jinhong Guo
Identification of Different Bile Species and Fermentation Times of Bile Arisaema Based on an Intelligent Electronic Nose and Least Squares Support Vector Machine.
Anal. Chem.: 2018, 90(5);3460-3466
[PubMed:29397686] [] [DOI] (I p)

Xiao-Jie Lu, Shao-Fei Chen, Xiang-Wei Xu, Dan Zhao, Hai-Feng Wang, Jiao Bai, Hui-Ming Hua, Gang Chen, Yue-Hu Pei
One pair of new cyclopentaisochromenone enantiomer from Alternaria sp. TNXY-P-1 and their cytotoxic activity.
J Asian Nat Prod Res: 2018, 20(4);328-336
[PubMed:28631515] [] [DOI] (I p)

Li-Xing Feng, Peng Sun, Tian Mi, Miao Liu, Wang Liu, Si Yao, Yi-Min Cao, Xiao-Lu Yu, Wan-Ying Wu, Bao-Hong Jiang, Min Yang, De-An Guo, Xuan Liu
Agglutinin isolated from Arisema heterophyllum Blume induces apoptosis and autophagy in A549 cells through inhibiting PI3K/Akt pathway and inducing ER stress.
Chin J Nat Med: 2016, 14(11);856-864
[PubMed:27914529] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects