Anemone raddeana

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Nomenclature

Other Names:

Historical Use of Anemone raddeana

Anemone raddeana in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Liangtoujian

Chinese Name  :

Common Name  :Radde anemone rhizome

Specific Name  : Rhizoma ahemones daddeanae

Scientific Name:
Collection  : The drug is collected in summer, removed from rootlet, washed clean and dried.

Description  : Long sub fusiform, acute and pointed at two ends, slightly curved and one end somewhat expanded. 1 - 3 cm long, 2 - 7 mm in diameter. Externally brown to brownish black with fine longitudinal wrinkles, the expanded portions usually possessing 1 - 3 rootlet scars appearing finned-protruding, occasionally with 3 - 5 indistinct annulations. Texture hard and fragile, easily broken, fracture slightly even, whitish or greyish brown, almost horny. Odourless, taste weak and then slightly bitter and pungent.

Identification  : 1.Transverse section: Epidermis consisting of 1 row of cells tangentially elongated, outer walls thickened. Cortex of 10 or more rows of sub rounded parenchymatous cells. Vascular bundles collateral, 10 or more ones arranged in a ring, phloem cells shrunken, xylem vessels 6 - 24, cambium ring indistinct. Rays broad pith relatively large and composed of sub rounded parenchymatous cells. Parenchymatous cells filled with starch granules.Powder: Greyish brown, starch granules numerous, simple granules sub rounded or elliptical, 2 - 11 µm in diameter. Hilum pointed or shortly cleft like, striations indistinct, compound granules of 2 - 4 components. Epidermal cells, reddish brown, yellow or bright yellow, the outer walls suberized and thickened, frequently protruding into the cell to be ridge like or tubercular. Reticular, spiral or scalariform vessels more frequent, 10 - 33 µm in diameter, some with bordered pitted vessels.2.Warm 2 g of the coarse powder in 10 ml of methanol on a water bath, shake for 10 minutes and filter. To 2 ml of the filtrate add 2 ml of 1% solution of sodium hydroxide and heat on a water bath for 3 minutes. The solution shows a clear bright yellow colour. Acidify with 1% hydrochloric acid solution, the bright yellow colour disappears and a turbid milk white colour is produced.3.Boil gently 1 g of the coarse powder with 10 ml of 70% ethanol on a water bath for 10 minutes and filter. Evaporate 2 ml of the filtrate to dryness and dissolve the residue in 1 ml of acetic anhydride. Add slowly sulfuric acid along the wall, a puirplish colour is produced at the junction of the layers. The upper layer shows a dark green colour on standing.

Processing  : Eliminate foreign matter, soak briefly, soften thoroughly, cut into thick slices and dry.Processed with salt: Stir fry the slices as described under the method for stir frying with salt (Appendix ll D) to dryness.

Action  : To relieve rheumatic conditions, and to cure carbuncle.

Indication  : rheumatoid arthritis with muscular contracture and joint pain; carbuncle with ulceration

Precautions  :

Dosage  : 1.5 to 3 g; appropriate quantity for external use.

Storage  : Preserve in a cool and dry place.

Synonymns for Anemone raddeana

Patent Medicines and Medicines with Multiple Ingredients that include Anemone raddeana

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Anemone raddeana in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Jesús Borrego, Herlinda Clement, Ligia-Luz Corrales-García, Iván Arenas, Gerardo Corzo
Key amino acid residues involved in mammalian and insecticidal activities of Magi4 and Hv1b, cysteine-rich spider peptides from the δ-atracotoxin family.
Amino Acids: 2020;
[PubMed:32067123] [WorldCat.org] [DOI] (I a)

Craig S Wilding, Nicola Fletcher, Eleanor K Smith, Peter Prentis, Gareth D Weedall, Zac Stewart
The genome of the sea anemone Actinia equina (L.): Meiotic toolkit genes and the question of sexual reproduction.
Mar Genomics: 2020;100753
[PubMed:32057717] [WorldCat.org] [DOI] (I a)

Xin Hu, Man Liu, Yifei Liu, Jingjing Zhang, Yuwen Tang, Hong Pei, Hegang Liu, Shilin Chen, Chengwu Song, Zhigang Hu
A two-step approach for systematic identification and quality evaluation of wild and introduced Anemone flaccida Fr. Schmidt (Di Wu) based on DNA barcode and UPLC-QTOF-MS/MS.
Anal Bioanal Chem: 2020;
[PubMed:32025771] [WorldCat.org] [DOI] (I a)

Lucas Leclère, Tal S Nir, Michael Bazarsky, Merav Braitbard, Dina Schneidman-Duhovny, Uri Gat
Dynamic evolution of the Cthrc1 genes, a newly defined collagen-like family.
Genome Biol Evol: 2020;
[PubMed:32022859] [WorldCat.org] [DOI] (I a)

Sha-Sha Wang, Shao-Yan Zhou, Xiao-Yan Xie, Ling Zhao, Yao Fu, Guang-Zhi Cai, Ji-Yu Gong
Comparison of the acute toxicity, analgesic and anti-inflammatory activities and chemical composition changes in Rhizoma anemones Raddeanae caused by vinegar processing.
BMC Complement Med Ther: 2020, 20(1);7
[PubMed:32020868] [WorldCat.org] [DOI] (I e)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects