Aloe barbadensis

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Nomenclature

Other Names:

Historical Use of Aloe barbadensis

Aloe barbadensis in Traditional Chinese Medicine

Background

Chinese Name (pinyin): Luhui

Chinese Name  :

Common Name  :Aloe

Specific Name  : Aloe

Scientific Name:
Collection  :

Description  : Old Aloes: Irregular pieces, often broken polygonal, varying in size, externally dark reddish-brown or dark-brown, lusterless. Texture light and hard, uneasily broken, fracture rough or with pockmarked striations, hygroscopic. Odour characteristic, taste: very bitter.New Aloes: Externally dark-brown, slightly green, lustrous. Texture light and lax, easily broken, fracture glassy with striations.

Identification  : 1.To 0.5g of the powder, add 50ml of water, shake thoroughly and filter. To 50ml of the filtrate add 0.2g of borax, heat to dissolve. To several drops of the solution add 30ml of water, mix well, a green fluorescence is produced. Examine under ultra-violet light (365nm), a light yellow fluorescence is produced. To 2ml of the filtrate, add 2ml of nitric acid, mix well, a brownish-red color is produced for Aloe barbadensis, and a yellowish-green color for Aloe ferax. To 2ml of the filtrate, add an equal volume of saturated bromine water, a yellow precipitate is produced.2.To 0.1g of the powder, add 5 ml of ferric chloride TS and 5ml of dilute hydrochloric acid, shake thoroughly, heat on a water bath for 5 minutes. Allow to cool add 10ml of carbon tetrachlorideand shake slowly for 1 minute. 6ml of carbon tetrachloride solution add 3ml of ammonia TS and shake, a rose-red to cherry-red color is produced in the ammonia layer.3.0.5g of the powder, add 20ml of methanol, boil on a water bath, shake for several minutes and filter. Use the filtrate as the test solution. Dissolve aloin CRS in mathanol to prepare a solution containing 5mg per ml as the reference solution. Carry out the method for, thin layer chromatography (Appendix Vl B), using silica gel G as the coating substance and ethyl acetate-methanol-water (100:17:13) as the mobile phase. Apply separately to the plate 5µl each of two solutions. After developing and removal of the plate, dry it in the air and spray with 10% solution of potassium hydroxide in methanol. Examine under-ultra violet light (365nm). A fluorescent spot in the chromatogram obtained with the test solution corresponds in position and color to the fluorescent spot in the chromatogram obtained with reference solution.Water: Carry out the determination of water (Appendix lX H, method 1) not more than 12.0%.Total Ash: Not more than 4.0% (Appendix lX K).Assay: Moisten 0.15g of Old Aloes or 0.2g of New Aloes powder (pass through No.5 sieve). Accurately weighed with 1ml of methanol in a 500ml volumetric flask, mix with 5ml of water previously warmed about 60ºC, add further 75ml of water at about 60ºC and shake for 30 minutes, cool, add water to volume, shake and filter. Discard the initial filtrate, transfer accurately 10ml of the successive filtrate to flask containing 1ml of 60% ferric chloride solution and 6ml of hydrochloric acid, heat under reflux on a water bath for 4 hours. Allow to cool, transfer the solution to a separator, wash the flask with 4ml of sodium hydroxide solution (1 mol/L) and 4ml of water in portions, combine the washings in the separator. Extract with 3 quantities each of 20ml of carbon tetrachloride, extract with 2 quantities, each of 10 ml of water, discard the water solution. Transfer the extracts to a 100ml volumetric flask, add carbon tetrachloride to volume and mix well. Evaporate carefully 20ml accurately measured on the water bath, add accurate 10ml of 0.5% solution of magnesium acetate in methanol to dissolve. Measure the absorbance at 512nm (Appendix VB). Calculate the content of C20H20O8, taking the 240 as the value of A (1%, 1cm).Old Aloes contains not less than 28.0% of anhydrous aloin.New Aloes not less than 18.0% calculated on the dried basis.

Processing  : Cut into small pieces.

Action  :

Indication  : constipation; infantile malnutrition due to improper feeding and convulsion external: eczema, tinea

Precautions  :

Dosage  :

Storage  :

Synonymns for Aloe barbadensis

Patent Medicines and Medicines with Multiple Ingredients that include Aloe barbadensis

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Aloe barbadensis in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials

Meta-Analysis

1st Five Results: pubmed search

Iqra Afzal, Sadia Zia, Shamaila Kausar, Ali Hazrat, Tour Jan, Madeeha Anwar, Muhammad Riaz, Fahad Said Khan, Muhammad Akram, Ghulam Rasool
Dose Response Relationship of Aloe vera to Cure Atopic Dermatitis in Rats.
Dermatol Ther: 2020;e13376
[PubMed:32246552] [WorldCat.org] [DOI] (I a)

Sunanda Panda, Rajesh Sharma, Aarif Khan, Anand Kar
##Title##
Mol. Biol. Rep.: 2020;
[PubMed:32242301] [WorldCat.org] [DOI] (I a)

Wenpeng Ma, Chengcheng Liu, Jiao Li, Ming Hao, Yanhong Ji, Xiaoyan Zeng
The effects of aloe emodin-mediated antimicrobial photodynamic therapy on drug-sensitive and resistant Candida albicans.
Photochem. Photobiol. Sci.: 2020;
[PubMed:32232258] [WorldCat.org] [DOI] (I a)

Fatemeh Ashkar, Shahla Rezaei, Sara Salahshoornezhad, Farhad Vahid, Maryam Gholamalizadeh, Samaneh Mirzaei Dahka, Saeid Doaei
The Role of medicinal herbs in treatment of insulin resistance in patients with Polycystic Ovary Syndrome: A literature review.
Biomol Concepts: 2020, 11(1);57-75
[PubMed:32229652] [WorldCat.org] [DOI] (I e)

Isabella Aquila, Cristoforo Ricci, Matteo Antonio Sacco, Santo Gratteri, Luigi De Aloe, Claudia Catia De Pasquale, Pietrantonio Ricci
The role of ethanethiol in deaths from acute poisoning by gas mixtures: A suicide case involving a decomposed corpse and a review of the literature.
Med Leg J: 2020;25817219891948
[PubMed:32228376] [WorldCat.org] [DOI] (I a)

Safety

Allergies

Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects