Alisma orientale

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Other Names:

Historical Use of Alisma orientale

Alisma orientale in Traditional Chinese Medicine


Yanzexie ÑÎÔóк Chinese Name (pinyin): Zexie

Chinese Name  :

Common Name  :Alismatis Rhizome

Specific Name  : Rhizoma alismatis

Scientific Name:
Collection  : The drug is collected in winter when stem turn withering, wash clean and dried and removed from the fibrous root and coarse outer tissue.

Description  : Subspherical, elliptical or ovate. 2 - 7 cm long, 2 - 6 cm in diameter. Externally yellowish white or yellowish brown with irregular transverse annular shallow furrows and numerous small raised fibrous root scars occasionally tuberculate bud scars attached to the base. Texture compact, fracture yellowish white, starchy with numerous small pores. Odour slight and taste slightly bitter.

Identification  : Powder: Yellowish brown, starch granules numerous, simple granules long ovoid, subspherical or ellipsoid, 3 - 14µm in diameter. Hilum V-shaped, shortly slit shaped or Y shaped, compound granules of 2 - 3 components. Parenchymatous cells subrounded with many elliptical pits crowded into pitted areas. Anticlinal walls of endodermis cells sinuous, somewhat relatively thick lignified with sparse and minute pit canals. Oil cavities mostly broken, whole ones subrounded, 54 - 110 µm in diameter. Sometimes oil drops contained in secretory cells visible.Total ash: Not more than 5% (Appendix lX K)Acid Insoluble ash: Not more than 5.0%

Processing  :

Action  : To cause diuresis , and to remove damp-heat.

Indication  : edema with oliguria; diarrhea with oliguria; vertigo due to retention of fluid; acute urinary tract infection with difficult painful urination; hyperlipemia

Precautions  :

Dosage  : 6 to 9 g.

Storage  : Preserve in a dry place, protected from moth.

Synonymns for Alisma orientale

Patent Medicines and Medicines with Multiple Ingredients that include Alisma orientale

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Alisma orientale in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Cheng-Peng Sun, Juan Zhang, Wen-Yu Zhao, Jing Yi, Jian-Kun Yan, Ya-Li Wang, Christophe Morisseau, Zhong-Bo Liu, Bruce D Hammock, Xiao-Chi Ma
Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials and molecular dynamics.
Bioorg. Chem.: 2020, 96;103637
[PubMed:32032849] [] [DOI] (I a)

Jia-Xiang Chen, Hai-Yan Li, Tian-Tian Li, Wen-Cheng Fu, Xin Du, Chun-Hui Liu, Wen Zhang
Alisol A-24-acetate promotes glucose uptake via activation of AMPK in C2C12 myotubes.
BMC Complement Med Ther: 2020, 20(1);22
[PubMed:32020870] [] [DOI] (I e)

Na Yang, Ya-Qian Dong, Meng-Fan Wu, Shan-Ze Li, Hong-Xin Yu, Shen-Shen Yang
Establishing a rapid classification and identification method for the major triterpenoids of Alisma orientale.
Phytochem Anal: 2019;
[PubMed:31880044] [] [DOI] (I a)

Tuan-Tuan Wang, Bei-Bei Li, Sai Wang, Pei Hua, Jun Chen, Guang-Guo Ying
Huan Jing Ke Xue: 2019, 40(12);5394-5400
[PubMed:31854611] [] [DOI] (P p)

Rong Tian, Wei Gu, Yuchen Gu, Chao Geng, Fei Xu, Qinan Wu, Jianguo Chao, Wenda Xue, Chen Zhou, Fan Wang
Methyl jasmonate promote protostane triterpenes accumulation by up-regulating the expression of squalene epoxidases in Alisma orientale.
Sci Rep: 2019, 9(1);18139
[PubMed:31792343] [] [DOI] (I e)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects