Akebia quinata

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Other Names:

Historical Use of Akebia quinata

Akebia quinata in Traditional Chinese Medicine


Chinese Name (pinyin): Yuzhizi

Chinese Name  :

Common Name  :Akebia Fruit

Specific Name  : Fructus akebiae

Scientific Name:
Collection  : The drug is collected in summer or autumn when the fruit turned, greenish yellow, dried in the sun or treated in boiling water for a moment and dried in the sun.

Description  : Reniform or prolate-ellipsoidal, slightly curved, 3 - 9cm long, 1.5 - 3.5cm in diameter. Externally yellowish brown with deep irregular wrinkles. Apex obtuse exhibiting a fruit stalk scar at the base. Texture hard, sarcocarp pale yellow or yellowish brown, seeds numerous, flattened and prolate-ovoid, yellowish brown or purplish brown, lustrous and linearly striated. Odor slightly aromatic, taste bitter.

Identification  : Wash clean, dry in the sun and brak to pieces before use.

Processing  :

Action  : To regulate the flow of the liver qi, to promote blood circultaion and relieve pain, and to cause diuresis.

Indication  :

Precautions  :

Dosage  : 3 to 9 g.

Storage  : Preserve in a ventilated dry place.

Synonymns for Akebia quinata

Patent Medicines and Medicines with Multiple Ingredients that include Akebia quinata

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Akebia quinata in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Sun Haeng Park, Seol Jang, Si Woo Lee, Sun Dong Park, Yoon-Young Sung, Ho Kyoung Kim
Akebia quinata Decaisne aqueous extract acts as a novel anti-fatigue agent in mice exposed to chronic restraint stress.
J Ethnopharmacol: 2018, 222;270-279
[PubMed:29630998] [WorldCat.org] [DOI] (I p)

Sang Hoon Lee, Young Sun Song, Yoonhwa Jeong, Kwang Suk Ko
Antioxidative and Anti-Inflammatory Activities of Akebia quinata Extracts in an In Vitro Model of Acute Alcohol-Induced Hepatotoxicity.
J Med Food: 2017, 20(9);912-922
[PubMed:28816585] [WorldCat.org] [DOI] (I p)

Gyeong-Ji Kim, Da Hye Song, Han Seok Yoo, Kang-Hyun Chung, Kwon Jai Lee, Jeung Hee An
Hederagenin Supplementation Alleviates the Pro-Inflammatory and Apoptotic Response to Alcohol in Rats.
Nutrients: 2017, 9(1);
[PubMed:28067819] [WorldCat.org] [DOI] (I e)

Jin-Pyo An, Thi Kim Quy Ha, Jinwoong Kim, Tae Oh Cho, Won Keun Oh
Protein Tyrosine Phosphatase 1B Inhibitors from the Stems of Akebia quinata.
Molecules: 2016, 21(8);
[PubMed:27548130] [WorldCat.org] [DOI] (I e)

Jeong-Sook Shin, Lei Peng, Kyungsu Kang, Yongsoo Choi
Direct analysis of prostaglandin-E2 and -D2 produced in an inflammatory cell reaction and its application for activity screening and potency evaluation using turbulent flow chromatography liquid chromatography-high resolution mass spectrometry.
J Chromatogr A: 2016, 1463;128-35
[PubMed:27524299] [WorldCat.org] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects