Agrimonia pilosa

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Other Names:

Historical Use of Agrimonia pilosa

Agrimonia pilosa in Traditional Chinese Medicine


Chinese Name (pinyin): Xianhecao

Chinese Name  :

Common Name  :Agrimony

Specific Name  : Herba agrimoniae

Scientific Name:
Collection  : The drug is collected in summer and autumn when foliage branched growing luxuriantly. Remove from foreign matter and dried.

Description  : The drug 50 - 100cm long with white hairs. The lower part of the stem cylindrical, 4- 6mm in diameter, reddish brown, the upper part square, the four sides slightly depressed, greenish brown, gloved longitudinally and ribbed, nodose, texture light and hard, easily broken, fracture hollowed. Leaves odd-pinnate, dark-green, crumpled and rolled,.Texture fragile, easily broken, leaflets of two sizes, the small leaflets interposed between the large ones at the leaf axis and the ones at the apex relatively large when whole, ovate or long elliptical, acute at the apex, cuneate at the base, margin serrate, stipules 2, amplexicaul, oblique ovate. Racene slender, the lower part of calyx tubular with hook bristles at the upper part of calyx tube, 5 - lobbed at the apex, petals yellow, odor slight, taste slightly bitter.

Identification  : Powder, dark green. The cells of the upper epidermis polygonal and walls of the lower epidermis sinuous, stomata anomocytic or anisocytic. Non-glandular hairs unicellular, varying in length, walls thickened and lignified with warty and infrequent spiral striations. Small glandular hairs composed of an ovoid, 1 - 4 celled head and 1 - 2 celled stalk, a few glandular scales present, composed of a unicellular head up to 68µm in diameter, containing volatile oil drops and unicellular stalk. Cluster of calcium oxalate fairly abundant, 9 - 50µm in diameter.

Processing  : Remove remains of roots and foreign matter, wash clean, soften briefly, cut into sections and dry.

Action  : To arrest bleeding, to stop malarial attacks, to relieve dysentary, and to counteract toxicity.

Indication  : hemoptysis, hematemesis, abnormal uterine bleeding; malaria; dysentery with bloody stools; overexertion; boils and sores; pubal itching with excessive leukorrhea

Precautions  :

Dosage  : 6 to 12 g; appropriate quantity for external use.

Storage  : Preserve in a ventilated and dry place.

Synonymns for Agrimonia pilosa

Patent Medicines and Medicines with Multiple Ingredients that include Agrimonia pilosa

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Agrimonia pilosa in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Wei Huang, Shengyang Jin, Wenbo Yang, Shuo Tian, Chunqing Meng, Huan Deng, Hong Wang
Protective effect of Agrimonia pilosa polysaccharides on dexamethasone-treated MC3T3-E1 cells via Wnt/β-Catenin pathway.
J. Cell. Mol. Med.: 2020, 24(3);2169-2177
[PubMed:31957180] [] [DOI] (I p)

Ping-Ping Guo, Wei Shui, Cong Jiang, Xiao-Mei Jian, Su-Feng Zhu, Yong-Yong Zhang, Jie Feng, Yi-Ping Chen
[Niche characteristics of understory dominant species of talus slope in degraded tiankeng]. [退化天坑倒石坡林下优势物种生态位特征.]
Ying Yong Sheng Tai Xue Bao: 2019, 30(11);3635-3645
[PubMed:31833675] [] [DOI] (P p)

Wei Huang, Shengyang Jin, Wenbo Yang, Shuo Tian, Chunqing Meng, Huan Deng, Chong Wang, Hong Wang
Agrimonia pilosa polysaccharide and its sulfate derives facilitate cell proliferation and osteogenic differentiation of MC3T3-E1 cells by targeting miR-107.
Int. J. Biol. Macromol.: 2019;
[PubMed:31786295] [] [DOI] (I a)

Hyun Woo Kim, Seong Yeon Choi, Hyeon Seok Jang, Byeol Ryu, Sang Hyun Sung, Heejung Yang
Exploring novel secondary metabolites from natural products using pre-processed mass spectral data.
Sci Rep: 2019, 9(1);17430
[PubMed:31758082] [] [DOI] (I e)

Jeong Eun Kwon, Yeong-Geun Lee, Ji-Hun Kang, Yun-Feng Bai, Yong Joon Jeong, Nam-In Baek, Young-Jin Seo, Se Chan Kang
Anti-viral activity of compounds from Agrimonia pilosa and Galla rhois extract mixture.
Bioorg. Chem.: 2019, 93;103320
[PubMed:31585267] [] [DOI] (I p)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects