Acanthopanax gracilistylus

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Other Names:

Historical Use of Acanthopanax gracilistylus

Acanthopanax gracilistylus in Traditional Chinese Medicine


Chinese Name (pinyin): Wujiapi

Chinese Name  :

Common Name  :Acanthopanax Bark

Specific Name  : Cortex acanthopanacis

Scientific Name:
Collection  : The root is collected in summer and autumn, wash clean, the bark stripped from the root and dried in the sun.

Description  : Irregular quills, 5-15cm long, 0.4-1.4cm in diameter, about 2mm thick. Outer surface greyish-brown with a slightly twisted longitudinal wrinkles and tranverse lenticels, inner surface pale yellow or greyoish yellow with fine longitudinal wrinkles. Texture light fragile, easily broken, fracture irregular, greyish white, odour slightly aromatic, taste slightly pungent and bitter.Identification: transverse section, cork cells several layers, cortex narrow scattered with few secretory canals. Phoem broad with cleft in the outer part and rays 1-5 cells wide, secretory canals fairly frequent subrounded by 4-11 secretory cells. Parenchymatous cells containing clusters of calcium oxalate 8-64µm in diameter, sometimes the crystal cells linked together with clusters arranged in rows. Cork cells rectangular or polygonal, thin walled. Sometimes the wall of the cork cells of older root barks unevenly thickened, less pitted. Fragments of secretory canals containing colourless opr pale yellow secretion. Starch granules abundant, simple granules polygonal or subspherical, 2-8µm in diameter, compound granules consisting of 2 to numerous components.

Identification  :

Processing  : Eliminate foreign matter, wash clean, soften thoroughly, cut into thick slices and dry in the sun.

Action  : To relieve rehumatic conditions, and tonify the liver and the kidney, and strengthen the tendons and bones.

Indication  : rheumatic or rheumatoid arthralgia with flaccid extremities; retarded walking and lack of strenght in children; edema

Precautions  :

Dosage  : 4.5 to 9 g.

Storage  : Preserve in a dry place, protected from mould and moth.

Synonymns for Acanthopanax gracilistylus

Patent Medicines and Medicines with Multiple Ingredients that include Acanthopanax gracilistylus

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of Acanthopanax gracilistylus in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Kuba Adamczyk, Marta Olech, Jagoda Abramek, Wioleta Pietrzak, Rafał Kuźniewski, Anna Bogucka-Kocka, Renata Nowak, Aneta A Ptaszyńska, Alina Rapacka-Gackowska, Tomasz Skalski, Maciej Strzemski, Ireneusz Sowa, Magdalena Wójciak-Kosior, Marcin Feldo, Daniel Załuski
Oxid Med Cell Longev: 2019, 2019;8673521
[PubMed:30984341] [] [DOI] (I e)

Hong-Bo Xu, Tong-Hua Yang, Pei Xie, Zhi-Shu Tang, Xiao Song, Huai-Li Xu, Yan-Hong Li, Dong-Bo Zhang, Yan-Ru Liu, Yan-Ni Liang, Yu Zhang, Shi-Jun Liu, Si-Min Wei, Chen Sun, Hong-Bo Liu, Chong Deng, Wei Wang
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities.
Fitoterapia: 2018, 130;265-271
[PubMed:30243779] [] [DOI] (I p)

Man-Xia Lu, Yang Yang, Qin-Peng Zou, Jiao Luo, Bin-Bei Zhang, Xiang-Qian Liu, Eun-Hee Hwang
Anti-Diabetic Effects of Acankoreagenin from the Leaves of Acanthopanax Gracilistylus Herb in RIN-m5F Cells via Suppression of NF-κB Activation.
Molecules: 2018, 23(4);
[PubMed:29671829] [] [DOI] (I e)

Eman A Salem, Sabah M Ebrahem
Psychosocial work environment and oxidative stress among nurses'.
J Occup Health: 2018, 60(2);182-191
[PubMed:29311439] [] [DOI] (I p)

Xiao-Jun Li, Qin-Peng Zou, Xiang Wang, Kwan-Woo Kim, Mao-Fang Lu, Sung-Kwon Ko, Chang-Soo Yook, Youn-Chul Kim, Xiang-Qian Liu
Lupane Triterpenes from the Leaves of Acanthopanax gracilistylus.
Molecules: 2018, 23(1);
[PubMed:29301264] [] [DOI] (I e)



Side Effect and Warnings

Pregnancy and Breastfeeding

Adverse Effects