45 substances

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45 substances is a non-scientific common name that may refer to a number of plant species and varieties.


Other Names:

Historical Use of 45 substances

45 substances in Traditional Chinese Medicine


Historical Use of 45 substances in Western Medicine

Quote Paraph: "The pharmacological methods employed to achieve these ends were discussed by Temkin (1971), who based his account on material available in the great Herbal of Dioscurides. This contained descriptions of 45 substances with alleged antiepileptic properties.
Sec Auth: Eadie MJ and Bladin PF
Title: A Disease Once Sacred. John Libbey & Company Ltd, 2001
Page: 176
Source: A Disease Once Sacred, John Libbey & Company Ltd, 2001, M.J. Eadie and P.F. Bladin Eadie
Complete: Eadie MJ, Bladin PF. A disease once sacred: a history of the medical understanding of epilepsy. Eastleigh: John Libbey; 2001. p. 176.
Primary Source: Herbal of Dioscurides


Synonymns for 45 substances

Patent Medicines and Medicines with Multiple Ingredients that include 45 substances

Pharmaceutical Information

Chemical Constituents

Evidence or the Use of 45 substances in the Treatment of Epilepesy

Basic Science

Animal Studies

Cohort, Case-Control and Non-Randomized Trials

Randomized Controlled Trials


1st Five Results: pubmed search

Z Erisgin, Y Tekelioglu
Flow cytometric examination of apoptotic effect on brain tissue in postnatal period created by intrauterine oxcarbazepine and gabapentin exposure.
Bratisl Lek Listy: 2017, 118(2);107-111
[PubMed:28814092] [WorldCat.org] [DOI] (P p)

Filiz Tubaş, Sedat Per, Abdulkadir Taşdemir, Ayşe Kaçar Bayram, Mehmet Yıldırım, Aydın Uzun, Recep Saraymen, Hakan Gümüş, Ferhan Elmalı, Hüseyin Per
Effects of Cornus mas L. and Morus rubra L. extracts on penicillin-induced epileptiform activity: an electrophysiological and biochemical study.
Acta Neurobiol Exp (Wars): 2017, 77(1);45-56
[PubMed:28379215] [WorldCat.org] [DOI] (I p)

Vinay Kumar, Sandeep Kumar Sharma, K Nagarajan, Praveen Kumar Dixit
Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice.
Iran J Med Sci: 2016, 41(5);430-6
[PubMed:27582593] [WorldCat.org] (P p)

Krzysztof Kamiński, Beata Wiklik, Jolanta Obniska
Synthesis, anticonvulsant properties, and SAR analysis of differently substituted pyrrolidine-2,5-diones and piperidine-2,6-diones.
Arch. Pharm. (Weinheim): 2014, 347(11);840-52
[PubMed:25196991] [WorldCat.org] [DOI] (I p)

Devender Bhalla, Pierre-Marie Preux, Claude Mignard, Didier Smadja, Achille Edem Tchalla, Benoît Marin, Pierre Jallon
Newly-diagnosed epileptic seizures in three populations: Geneva (EPIGEN), Martinique (EPIMART), and the Reunion Island (EPIREUN).
Epileptic Disord: 2013, 15(3);243-54
[PubMed:23996651] [WorldCat.org] [DOI] (P p)



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